SCHEMBL20923142

SCHEMBL20923142

N#Cc1ccc(-c2ccc3c(c2)c2ccccc2n3-c2cc(-c3ccncc3)c(C#N)cc2-c2ccccc2)c(C#N)c1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.38
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38
STS P08842 1/20 0.36
PIK3CA P42336 1/20 0.34
FLT3 P36888 2/20 0.34
SQOR Q9Y6N5 1/20 0.34
XDH P47989 1/20 0.34
PTGER4 P35408 1/20 0.34
LRRK2 Q5S007 1/20 0.33
MAPK13 O15264 1/20 0.33
RAF1 P04049 1/20 0.33
MAPK12 P53778 1/20 0.33
MAPK11 Q15759 1/20 0.33
MAPK14 Q16539 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20923144 0.97 CYP19A1 (0.40) CYP19A1CYP11B1CYP11B2STSPIK3CA
SCHEMBL20924090 0.94 CYP19A1 (0.38) CYP19A1CYP11B1CYP11B2STSFLT3
SCHEMBL19919765 0.94 STS (0.38) CYP19A1CYP11B1CYP11B2STSFLT3
SCHEMBL20923277 0.93 CYP19A1 (0.40) CYP19A1CYP11B1CYP11B2STSPIK3CA
SCHEMBL19909006 0.93 STS (0.38) CYP19A1CYP11B1CYP11B2STSFLT3
SCHEMBL20923543 0.93 CYP19A1 (0.39) CYP19A1CYP11B1CYP11B2FLT3SQOR
SCHEMBL20923264 0.92 PIK3CA (0.40) CYP19A1CYP11B1CYP11B2PIK3CAFLT3
SCHEMBL20924092 0.91 CYP19A1 (0.40) CYP19A1CYP11B1CYP11B2STSPIK3CA
SCHEMBL20923147 0.91 PDE10A (0.38) CYP19A1PIK3CASQOR
SCHEMBL20924122 0.90 FLT3 (0.38) CYP19A1CYP11B1CYP11B2STSFLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3266772-B1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2019-04-24 EP disclosed