Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.60 |
| ▸ | AOC3 | Q16853 | 17/20 | 0.57 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18976723 | 0.90 | AOC3 (0.68) | KCNH2AOC3 | |
| SCHEMBL20924385 | 0.89 | AOC3 (0.62) | KCNH2AOC3 | |
| SCHEMBL20924324 | 0.88 | AOC3 (0.54) | KCNH2AOC3JAK2ROCK2MAP4K4 | |
| SCHEMBL20924446 | 0.88 | AOC3 (0.59) | KCNH2AOC3 | |
| SCHEMBL18976977 | 0.86 | AOC3 (0.54) | KCNH2AOC3JAK2ROCK2MAP4K4 | |
| SCHEMBL20924362 | 0.85 | AOC3 (0.57) | KCNH2AOC3 | |
| SCHEMBL20924303 | 0.84 | AOC3 (0.57) | KCNH2AOC3 | |
| SCHEMBL22997070 | 0.82 | AOC3 (0.52) | KCNH2AOC3 | |
| SCHEMBL20924390 | 0.81 | AOC3 (0.61) | KCNH2AOC3 | |
| SCHEMBL18976721 | 0.79 | AOC3 (0.66) | KCNH2AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970260-B1 | IMIDAZO[4,5-C]PYRIDINE AND PYRROLO[2,3-C]PYRIDINE DERIVATIVES AS SSAO INHIBITORS | PROXIMAGEN LLC (US) | 2019-04-24 | — | — | EP | disclosed |