Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 18/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | CLK2 | P49760 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20924316 | 0.91 | AOC3 (0.54) | AOC3KCNH2 | |
| SCHEMBL20924435 | 0.86 | KCNH2 (0.60) | AOC3KCNH2JAK2ROCK2MAP4K4 | |
| SCHEMBL20924505 | 0.85 | AOC3 (0.64) | AOC3KCNH2 | |
| SCHEMBL20924378 | 0.84 | AOC3 (0.75) | AOC3KCNH2 | |
| SCHEMBL21253848 | 0.83 | AOC3 (0.56) | AOC3KCNH2 | |
| SCHEMBL18976983 | 0.83 | AOC3 (0.61) | AOC3KCNH2JAK2ROCK2MAP4K4 | |
| SCHEMBL20924385 | 0.83 | AOC3 (0.62) | AOC3KCNH2 | |
| SCHEMBL20924441 | 0.77 | AOC3 (0.57) | AOC3KCNH2 | |
| SCHEMBL18976723 | 0.76 | AOC3 (0.68) | AOC3KCNH2 | |
| SCHEMBL20924446 | 0.76 | AOC3 (0.59) | AOC3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017098236-A1 | VAP-1 INHIBITORS FOR TREATING PAIN | PROXIMAGEN LIMITED (GB) | 2017-06-15 | — | — | WO | disclosed |