Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.58 |
| ▸ | PEPD | P12955 | 1/20 | 0.46 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 4/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | BCR | P11274 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15692966 | 0.88 | PIN1 (0.46) | PIN1PEPDXPNPEP1DPP4DPP8 | |
| SCHEMBL15746341 | 0.88 | PIN1 (0.46) | PIN1PEPDXPNPEP1DPP4DPP8 | |
| SCHEMBL18018536 | 0.88 | PIN1 (0.46) | PIN1PEPDXPNPEP1DPP4DPP8 | |
| SCHEMBL5203233 | 0.88 | PIN1 (0.54) | PIN1PEPDXPNPEP1ELANE | |
| SCHEMBL10281126 | 0.86 | PIN1 (0.47) | PIN1PEPDXPNPEP1DPP4DPP8 | |
| SCHEMBL10281125 | 0.86 | PIN1 (0.47) | PIN1PEPDXPNPEP1DPP4DPP8 | |
| SCHEMBL5991676 | 0.86 | PEPD (0.45) | PIN1PEPDXPNPEP1DPP4DPP8 | |
| SCHEMBL13014715 | 0.86 | PIN1 (0.44) | PIN1PEPDXPNPEP1CYP3A4CYP2C9 | |
| SCHEMBL10140557 | 0.83 | PIN1 (0.40) | PIN1PEPDXPNPEP1DPP4DPP8 | |
| SCHEMBL15765617 | 0.83 | PIN1 (0.40) | PIN1PEPDXPNPEP1DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3473639-A1 | HEPATITIS C VIRUS INHIBITOR AND APPLICATION | Zhejiang Palo Alto Pharmaceuticals, Inc (CN) | 2019-04-24 | — | — | EP | disclosed |