Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10188491 | 0.89 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1HTTHPGDMEN1 | |
| Hydrochloric Acid SCHEMBL30969161 | 0.88 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1HTTHPGDMEN1 | |
| SCHEMBL21048180 | 0.88 | HPGD (0.51) | SMN1; SMN2ALDH1A1HTTHPGDMEN1 | |
| SCHEMBL23223242 | 0.87 | HTT (0.46) | SMN1; SMN2ALDH1A1HTTHPGDMEN1 | |
| SCHEMBL10188494 | 0.87 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1HTTHPGDMEN1 | |
| SCHEMBL16587527 | 0.86 | MEN1 (0.44) | SMN1; SMN2ALDH1A1HTTHPGDMEN1 | |
| SCHEMBL22605580 | 0.86 | HTT (0.41) | SMN1; SMN2ALDH1A1HTTHPGDMEN1 | |
| SCHEMBL24262587 | 0.85 | SGMS2 (0.49) | SMN1; SMN2ALDH1A1HTTHPGDMEN1 | |
| SCHEMBL22049534 | 0.84 | HTT (0.50) | SMN1; SMN2ALDH1A1HTTHPGDMEN1 | |
| SCHEMBL24262612 | 0.83 | NPC1 (0.45) | SMN1; SMN2ALDH1A1HTTHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3473629-A1 | METHOD FOR PRODUCING SUBSTITUTED POLYCYCLIC PYRIDONE DERIVATIVE AND CRYSTAL OF SAME | Shionogi & Co., Ltd. (JP) | 2019-04-24 | — | — | EP | disclosed |