SCHEMBL20924754

SCHEMBL20924754

O=COCCOC(=O)CCC(=O)OCN1C(=O)c2ccccc2C1=O

nearest known ligand 0.63

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.53
CYP3A4 P08684 1/20 0.53
CYP2C19 P33261 1/20 0.53
ALDH1A1 P00352 7/20 0.48
KMT2A Q03164 3/20 0.46
TSHR P16473 2/20 0.46
HPGD P15428 1/20 0.46
MEN1 O00255 2/20 0.45
HSD17B10 Q99714 1/20 0.45
NPSR1 Q6W5P4 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27352834 0.85 CYP1A2 (0.67) CYP1A2CYP3A4CYP2C19ALDH1A1KMT2A
SCHEMBL20924697 0.81 CYP2C19 (0.53) CYP1A2CYP3A4CYP2C19ALDH1A1KMT2A
SCHEMBL27352835 0.80 CYP1A2 (0.64) CYP1A2CYP3A4CYP2C19ALDH1A1KMT2A
SCHEMBL11887994 0.79 CYP1A2 (0.51) CYP1A2CYP3A4CYP2C19ALDH1A1KMT2A
SCHEMBL24688014 0.77 CYP1A2 (0.60) CYP1A2CYP3A4CYP2C19ALDH1A1KMT2A
SCHEMBL9596654 0.76 CA12 (0.46) ALDH1A1KMT2ATSHRMEN1HSD17B10
SCHEMBL19667893 0.73 ALDH1A1 (0.62) CYP1A2CYP3A4CYP2C19ALDH1A1KMT2A
SCHEMBL29783045 0.73 ALDH1A1 (0.62) CYP1A2CYP3A4CYP2C19ALDH1A1KMT2A
SCHEMBL30855594 0.71 CYP1A2 (0.57) CYP1A2CYP3A4CYP2C19ALDH1A1KMT2A
SCHEMBL7346924 0.71 CYP1A2 (0.57) CYP1A2CYP3A4CYP2C19ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2781959-B1 Radiation-sensitive resin composition, method for forming resist pattern, polymer and polymerizable compound JSR CORP (JP) 2019-04-24 EP disclosed