SCHEMBL20924801

SCHEMBL20924801

NC(=O)C(N)CCC(O)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.37
BLM P54132 1/20 0.37
PMP22 Q01453 1/20 0.37
KMT2A Q03164 1/20 0.37
CYP1A2 P05177 2/20 0.33
GSR P00390 2/20 0.33
GRM8 O00222 1/20 0.33
GRM6 O15303 1/20 0.33
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33
GRIK1 P39086 1/20 0.33
GRM5 P41594 1/20 0.33
GRIA1 P42261 1/20 0.33
GRIA2 P42262 1/20 0.33
GRIA3 P42263 1/20 0.33
SLC1A3 P43003 1/20 0.33
SLC1A2 P43004 1/20 0.33
SLC1A1 P43005 1/20 0.33
GRIA4 P48058 1/20 0.33
GRIN1 Q05586 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19696553 1.00 ALOX15 (0.37) ALOX15BLMPMP22KMT2ACYP1A2
SCHEMBL15676365 0.88 ALOX15 (0.43) ALOX15BLMPMP22KMT2ACYP1A2
SCHEMBL17541311 0.88 ALOX15 (0.43) ALOX15BLMPMP22KMT2ACYP1A2
SCHEMBL14956926 0.88 ALOX15 (0.43) ALOX15BLMPMP22KMT2ACYP1A2
SCHEMBL7028368 0.84 GSR (0.38) ALOX15BLMPMP22KMT2ACYP1A2
SCHEMBL6284571 0.84 GSR (0.38) ALOX15BLMPMP22KMT2ACYP1A2
SCHEMBL7024901 0.84 GSR (0.38) ALOX15BLMPMP22KMT2ACYP1A2
SCHEMBL15778941 0.78 KMT2A (0.61) ALOX15BLMPMP22KMT2ACYP1A2
SCHEMBL17227466 0.78 GSR (0.56) ALOX15BLMPMP22KMT2ACYP1A2
SCHEMBL15778940 0.78 KMT2A (0.61) ALOX15BLMPMP22KMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3473273-A1 SELECTIVE DELIVERY MOLECULES AND METHODS OF USE Avelas Biosciences, Inc. (US) 2019-04-24 EP disclosed