Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19882268 | 1.00 | TDP1 (0.50) | TDP1POLBAPEX1HTTMAPT | |
| SCHEMBL803172 | 0.94 | TDP1 (0.56) | TDP1POLBAPEX1HTTMAPT | |
| SCHEMBL19978522 | 0.92 | POLB (0.59) | TDP1POLBAPEX1HTTMAPT | |
| SCHEMBL17070343 | 0.91 | TDP1 (0.53) | TDP1POLBAPEX1HTTMAPT | |
| SCHEMBL12592442 | 0.91 | POLB (0.61) | TDP1POLBAPEX1HTTMAPT | |
| SCHEMBL19799417 | 0.91 | POLB (0.61) | TDP1POLBAPEX1HTTMAPT | |
| SCHEMBL31520182 | 0.91 | POLB (0.61) | TDP1POLBAPEX1HTTMAPT | |
| SCHEMBL23137082 | 0.90 | TDP1 (0.52) | TDP1POLBAPEX1HTTMAPT | |
| SCHEMBL17488397 | 0.90 | TDP1 (0.52) | TDP1POLBAPEX1HTTMAPT | |
| SCHEMBL21091143 | 0.90 | POLB (0.52) | TDP1POLBAPEX1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024133363-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2024-06-27 | — | — | WO | disclosed |
| WO-2023094404-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2023-06-01 | — | — | WO | disclosed |
| WO-2023066827-A1 | LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2023-04-27 | — | — | WO | disclosed |
| WO-2022002997-A1 | LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2022-01-06 | — | — | WO | disclosed |
| EP-3257916-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2021-11-17 | — | — | EP | disclosed |
| US-20210348056-A1 | Polymerisable Compounds and the Use thereof in Liquid-Crystal Displays | MERCK PATENT GMBH (DE) | 2021-11-11 | — | — | US | disclosed |
| EP-3248061-B1 | LIGHT MODULATION ELEMENT | MERCK PATENT GMBH (DE) | 2020-10-14 | — | — | EP | disclosed |
| EP-3067406-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2019-04-24 | — | — | EP | disclosed |