SCHEMBL803172

SCHEMBL803172

C=C(C)C(=O)OCCCOc1ccc(C(=O)Oc2ccc(OC(=O)c3ccc(OCCCOC(=O)C(=C)C)cc3)c(C)c2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.56
POLB P06746 2/20 0.56
APEX1 P27695 1/20 0.56
HTT P42858 1/20 0.56
MAPT P10636 3/20 0.44
KMT2A Q03164 2/20 0.44
LMNA P02545 3/20 0.42
NPC1 O15118 2/20 0.42
CYP1A2 P05177 2/20 0.42
CYP2C9 P11712 2/20 0.42
CYP2C19 P33261 2/20 0.42
KDM4E B2RXH2 1/20 0.42
MAPK1 P28482 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
PPARG P37231 1/20 0.41
PPARD Q03181 1/20 0.41
PPARA Q07869 1/20 0.41
NFKB1 P19838 1/20 0.41
NFKB2 Q00653 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19978522 0.98 POLB (0.59) TDP1POLBAPEX1HTTMAPT
SCHEMBL17070343 0.97 TDP1 (0.53) TDP1POLBAPEX1HTTMAPT
SCHEMBL12592442 0.97 POLB (0.61) TDP1POLBAPEX1HTTMAPT
SCHEMBL31520182 0.97 POLB (0.61) TDP1POLBAPEX1HTTMAPT
SCHEMBL19799417 0.97 POLB (0.61) TDP1POLBAPEX1HTTMAPT
SCHEMBL23137082 0.96 TDP1 (0.52) TDP1POLBAPEX1HTTMAPT
SCHEMBL17488397 0.96 TDP1 (0.52) TDP1POLBAPEX1HTTMAPT
SCHEMBL21091143 0.96 POLB (0.52) TDP1POLBAPEX1HTTMAPT
SCHEMBL26032591 0.96 TDP1 (0.52) TDP1POLBAPEX1HTTMAPT
SCHEMBL14907480 0.96 POLB (0.52) TDP1POLBAPEX1HTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 609 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115322796-A Liquid crystal composition, moth eye film and preparation method thereof 上海先认新材料合伙企业(有限合伙) 2022-11-11 CN claimed
US-12043781-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
US-12043781-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
CN-118344882-A Method for improving stretchability of liquid crystal composition, liquid crystal composition and optical film 上海先幻高科新材料有限公司 2024-07-16 CN disclosed
WO-2024132893-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2024-06-27 WO disclosed
WO-2024126567-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2024-06-20 WO disclosed
CN-115368912-B Liquid crystal composition, reflective film and preparation method thereof 上海先认新材料合伙企业(有限合伙) 2024-05-14 CN disclosed
CN-115322796-B Liquid crystal composition, moth eye mask and preparation method of moth eye mask 上海先认新材料合伙企业(有限合伙) 2024-05-10 CN disclosed
US-20240067879-A1 Liquid-crystal medium MERCK PATENT GMBH (DE) 2024-02-29 US disclosed
US-20240067879-A1 Liquid-crystal medium MERCK PATENT GMBH (DE) 2024-02-29 US disclosed
WO-2011029510-A1 LIQUID-CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2011-03-17 WO disclosed
WO-2010133278-A1 LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2010-11-25 WO disclosed
US-20100272925-A1 LIQUID-CRYSTAL DISPLAY MERCK PATENT GESELLSCHAFT (DE) 2010-10-28 US disclosed
US-20100272925-A1 LIQUID-CRYSTAL DISPLAY MERCK PATENT GESELLSCHAFT (DE) 2010-10-28 US disclosed
EP-2243812-A2 Liquid crystal display Merck Patent GmbH (DE) 2010-10-27 EP disclosed
WO-2010089092-A1 LIQUID CRYSTALLINE MEDIUM AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2010-08-12 WO disclosed
US-20100103366-A1 Cyclohexylene Reactive Mesogens and Their Applications MERCK PATENT GMBH (DE) 2010-04-29 US disclosed
US-20100103366-A1 Cyclohexylene Reactive Mesogens and Their Applications MERCK PATENT GMBH (DE) 2010-04-29 US disclosed
WO-2008061606-A1 CYCLOHEXYLENE REACTIVE MESOGENS AND THEIR APPLICATIONS MERCK PATENT GMBH (DE) 2008-05-29 WO disclosed
EP-1887069-A1 Bicyclooctyl reactive mesogens MERCK PATENT GmbH (DE) 2008-02-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100272925-A1 LIQUID-CRYSTAL DISPLAY KLK3, BPHL, LPXN TDP1 2993/4885POLB 1907/4885APEX1 4248/4885
US-20100103366-A1 Cyclohexylene Reactive Mesogens and Their Applications CUTA, MC1R, CTSG TDP1 3193/4885POLB 1350/4885APEX1 1554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.