Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 7/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20912901 | 0.75 | CYP4F2 (0.46) | CYP4F2CYP4A11GAAHDAC3HDAC4 | |
| SCHEMBL2653067 | 0.67 | HDAC3 (0.51) | CYP4F2CYP4A11GAAMAPK1HDAC3 | |
| SCHEMBL23135913 | 0.66 | MAPK14 (0.39) | CYP4F2CYP4A11GAAHDAC3HDAC4 | |
| SCHEMBL19737212 | 0.66 | MAPK14 (0.41) | CYP4F2CYP4A11GAAHDAC3HDAC4 | |
| SCHEMBL12963136 | 0.64 | GAA (0.69) | GAAMAPK1HDAC3HDAC4HDAC1 | |
| SCHEMBL7836036 | 0.64 | CYP4A11 (0.44) | CYP4F2CYP4A11GAAMAPK1MAPT | |
| SCHEMBL16863717 | 0.64 | GAA (0.50) | GAAMAPK1HDAC3HDAC4HDAC1 | |
| SCHEMBL2653673 | 0.63 | HDAC3 (0.50) | CYP4F2CYP4A11GAAMAPK1HDAC3 | |
| SCHEMBL14586046 | 0.62 | MAPT (0.50) | GAAMAPK1HDAC3HDAC4HDAC1 | |
| SCHEMBL2654064 | 0.62 | POLB (0.49) | CYP4F2CYP4A11GAAHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3473628-A1 | DIHYDROPYRAZOLE AZEPINE COMPOUND SERVING AS AKT INHIBITOR | Medshine Discovery Inc. (CN) | 2019-04-24 | — | — | EP | disclosed |