Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17208375 | 0.94 | ALDH1A1 (0.41) | BCHEALDH1A1PKML3MBTL1MEN1 | |
| SCHEMBL17208378 | 0.94 | ALDH1A1 (0.41) | BCHEALDH1A1PKML3MBTL1MEN1 | |
| SCHEMBL2960396 | 0.92 | BCHE (0.49) | BCHEALDH1A1PKML3MBTL1MEN1 | |
| SCHEMBL2953586 | 0.88 | ALDH1A1 (0.44) | BCHEALDH1A1PKML3MBTL1MEN1 | |
| SCHEMBL623223 | 0.86 | ALDH1A1 (0.42) | BCHEALDH1A1PKML3MBTL1MEN1 | |
| SCHEMBL11980194 | 0.84 | BCHE (0.44) | BCHEALDH1A1PKML3MBTL1MEN1 | |
| SCHEMBL19380754 | 0.83 | BCHE (0.54) | BCHEALDH1A1PKML3MBTL1MEN1 | |
| SCHEMBL13201334 | 0.83 | ALDH1A1 (0.43) | BCHEALDH1A1PKMMEN1KMT2A | |
| SCHEMBL13450555 | 0.83 | ALDH1A1 (0.43) | BCHEALDH1A1PKMMEN1KMT2A | |
| SCHEMBL14492217 | 0.83 | ALDH1A1 (0.43) | BCHEALDH1A1PKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019079649-A1 | SUBSTITUTED PYRROLOPYRIDINES AS INHIBITORS OF ACTIVIN RECEPTOR-LIKE KINASE | BLUEPRINT MEDICINES CORPORATION (US) | 2019-04-25 | — | — | WO | disclosed |