SCHEMBL2092832

SCHEMBL2092832

CNc1cc(C)ccc1C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 2/20 0.56
GAA P10253 2/20 0.52
ALDH1A1 P00352 4/20 0.48
HTT P42858 2/20 0.48
KDM4E B2RXH2 2/20 0.48
TDP1 Q9NUW8 1/20 0.44
NPSR1 Q6W5P4 1/20 0.42
LMNA P02545 2/20 0.42
MEN1 O00255 1/20 0.42
HCRTR1 O43613 1/20 0.42
KMT2A Q03164 1/20 0.42
HDAC3 O15379 1/20 0.42
HDAC4 P56524 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC7 Q8WUI4 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC10 Q969S8 1/20 0.42
HDAC11 Q96DB2 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2858487 0.97 RAPGEF4 (0.54) RAPGEF4GAAALDH1A1HTTKDM4E
SCHEMBL29196035 0.81 RAPGEF4 (0.71) RAPGEF4GAAALDH1A1HTTKDM4E
SCHEMBL12889181 0.81 HPGD (0.45) RAPGEF4GAAALDH1A1HTTKDM4E
SCHEMBL9224102 0.81 GAA (0.65) RAPGEF4GAAALDH1A1HTTKDM4E
SCHEMBL1549143 0.79 RAPGEF4 (0.58) RAPGEF4GAAALDH1A1HTTTDP1
SCHEMBL10882869 0.77 GAA (0.55) RAPGEF4GAAALDH1A1HTTKDM4E
SCHEMBL2092830 0.77 RAPGEF4 (0.54) RAPGEF4GAAALDH1A1HTTKDM4E
SCHEMBL1485842 0.77 MAPT (0.47) RAPGEF4GAAALDH1A1HTTNPSR1
Hydrochloric Acid SCHEMBL2863950 0.77 RAPGEF4 (0.56) RAPGEF4GAAALDH1A1HTTTDP1
SCHEMBL12451042 0.77 GAA (0.55) RAPGEF4GAAALDH1A1HTTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114709420-B Modified polyimide secondary battery adhesive and preparation method thereof 江苏环峰电工材料有限公司 2023-11-14 CN claimed
EP-4676924-A1 CYCLIC NITROGEN COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES Merck Patent GmbH (DE) 2026-01-14 EP disclosed
WO-2025224262-A1 COMBINATION THERAPIES COMPRISING A CDK2 DEGRADER AND A CDK4/6 INHIBITOR MONTE ROSA THERAPEUTICS AG (CH) 2025-10-30 WO disclosed
EP-4608816-A1 COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF Monte Rosa Therapeutics AG (CH) 2025-09-03 EP disclosed
US-20250263395-A1 COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF MONTE ROSA THERAPEUTICS AG (CH) 2025-08-21 US disclosed
WO-2024184050-A1 CYCLIC NITROGEN COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2024-09-12 WO disclosed
WO-2024148308-A1 NOVEL, REVERSIBLE DPP1 INHIBITORS AND USES THEREOF INSMED INCORPORATED (US) 2024-07-11 WO disclosed
WO-2024118607-A1 COMPOUNDS, COMPOSITIONS, AND METHODS CHDI FOUNDATION, INC. (US) 2024-06-06 WO disclosed
WO-2024092039-A1 COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF MONTE ROSA THERAPEUTICS, INC. (US) 2024-05-02 WO disclosed
CN-114709420-B Modified polyimide secondary battery adhesive and preparation method thereof 江苏环峰电工材料有限公司 2023-11-14 CN disclosed
US-4605766-A REACTING AROMATIC AMINES WITH ETHERS IN PRESENCE OF CATALYST CONTAINING IRON OXIDE ETHYL CORPORATION (US) 1986-08-12 US disclosed
US-4599449-A POSSIBLE RECOVERY OF UNUSED ALCOHOL ETHYL CORPORATION (US) 1986-07-08 US disclosed
EP-0073277-B1 PROCESS FOR PRODUCING ORTHOALKYLATED AROMATIC AMINES MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1985-07-17 EP disclosed
EP-0148009-A2 Process for the alkylation of aromatic amines and use of the products thereof ETHYL CORPORATION (US) 1985-07-10 EP disclosed
EP-0073277-A1 Process for producing orthoalkylated aromatic amines MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1983-03-09 EP disclosed
US-4351958-A Process for producing orthoalkylated aromatic amine MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1982-09-28 US disclosed
US-4172944-A Water insoluble styryl dyestuffs having hetero-aryl methylene substituent BAYER AKTIENGESELLSCHAFT (DE) 1979-10-30 US disclosed
US-4115413-A ACID FREE BAYER AKTIENGESELLSCHAFT (DE) 1978-09-19 US disclosed
US-4046771-A GREENISH-YELLOW SHADES ON SYNTHETIC FIBERS BAYER AKTIENGESELLSCHAFT (DT) 1977-09-06 US disclosed
US-4016191-A WATER INSOLUBLE; LIGHTFASTNESS BAYER AKTIENGESELLSCHAFT (DT) 1977-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250263395-A1 COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF CDK2, SKP2, CDK1 RAPGEF4 2233/4885GAA 2291/4885ALDH1A1 3818/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.