Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.63 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31164748 | 0.96 | ESR2 (0.61) | NR1H2ESR2HDAC1TMEM97SIGMAR1 | |
| SCHEMBL20929548 | 0.82 | NR1H2 (0.65) | NR1H2ESR2HDAC1TMEM97SIGMAR1 | |
| SCHEMBL12359616 | 0.81 | CHRM4 (0.44) | NR1H2ESR2BRD4USP30HRH3 | |
| SCHEMBL20929267 | 0.81 | NR1H2 (0.64) | NR1H2ESR2HDAC1TMEM97SIGMAR1 | |
| SCHEMBL20929269 | 0.81 | NR1H2 (0.64) | NR1H2ESR2HDAC1TMEM97SIGMAR1 | |
| SCHEMBL1010120 | 0.81 | NR1H2 (0.63) | NR1H2ESR2HDAC1TMEM97SIGMAR1 | |
| SCHEMBL29506996 | 0.80 | NR1H2 (0.63) | NR1H2ESR2HDAC1TMEM97SIGMAR1 | |
| SCHEMBL26844994 | 0.80 | NR1H2 (0.63) | NR1H2ESR2HDAC1TMEM97SIGMAR1 | |
| SCHEMBL20929489 | 0.80 | NR1H2 (0.61) | NR1H2ESR2HDAC1TMEM97SIGMAR1 | |
| SCHEMBL4171451 | 0.79 | NR1H2 (0.64) | NR1H2ESR2HDAC1TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11459321-B2 | Broad spectrum antiviral compositions and methods | EVRYS BIO, LLC (US) | 2022-10-04 | — | — | US | disclosed |
| US-20210139475-A1 | Broad Spectrum Antiviral Compositions and Methods | EVRYS BIO, LLC (US) | 2021-05-13 | — | — | US | disclosed |
| WO-2019079519-A1 | BROAD SPECTRUM ANTIVIRAL COMPOSITIONS AND METHODS | FORGE LIFE SCIENCE, LLC (US) | 2019-04-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11459321-B2 | Broad spectrum antiviral compositions and methods | IRF3, MAVS, ZC3HAV1 | NR1H2 1472/4885ESR2 3487/4885HDAC1 183/4885 |
| US-20210139475-A1 | Broad Spectrum Antiviral Compositions and Methods | MAVS, IRF3, ZC3HAV1 | NR1H2 1583/4885ESR2 3095/4885HDAC1 174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.