Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 18/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20918119 | 0.83 | JAK1 (0.74) | JAK1STAT3 | |
| SCHEMBL30356216 | 0.83 | JAK1 (0.74) | JAK1STAT3 | |
| SCHEMBL20930670 | 0.81 | JAK1 (0.51) | JAK1 | |
| SCHEMBL20930234 | 0.76 | JAK1 (0.54) | JAK1 | |
| SCHEMBL20918015 | 0.75 | JAK1 (0.71) | JAK1 | |
| SCHEMBL30356056 | 0.75 | JAK1 (0.71) | JAK1 | |
| SCHEMBL20918456 | 0.74 | JAK1 (0.41) | JAK1 | |
| SCHEMBL20918792 | 0.73 | JAK1 (0.55) | JAK1JAK2 | |
| SCHEMBL30356243 | 0.73 | JAK1 (0.55) | JAK1JAK2 | |
| SCHEMBL20918455 | 0.72 | JAK1 (0.56) | JAK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019078619-A1 | HETEROCYCLIC COMPOUND AS A PROTEIN KINASE INHIBITOR | CJ HEALTHCARE CORPORATION (KR) | 2019-04-25 | — | — | WO | disclosed |