Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 15/20 | 0.45 |
| ▸ | JAK2 | O60674 | 13/20 | 0.45 |
| ▸ | JAK3 | P52333 | 4/20 | 0.42 |
| ▸ | TYK2 | P29597 | 3/20 | 0.42 |
| ▸ | STK10 | O94804 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MERTK | Q12866 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.42 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.42 |
| ▸ | ADCK1 | Q86TW2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20918455 | 0.86 | JAK1 (0.56) | JAK1JAK2JAK3TYK2STK10 | |
| SCHEMBL20918453 | 0.86 | JAK1 (0.48) | JAK1JAK2JAK3TYK2STK10 | |
| SCHEMBL20918792 | 0.75 | JAK1 (0.55) | JAK1JAK2JAK3 | |
| SCHEMBL30356243 | 0.75 | JAK1 (0.55) | JAK1JAK2JAK3 | |
| SCHEMBL30356056 | 0.73 | JAK1 (0.71) | JAK1ABL1 | |
| SCHEMBL20918015 | 0.73 | JAK1 (0.71) | JAK1ABL1 | |
| SCHEMBL20930670 | 0.73 | JAK1 (0.51) | JAK1MERTK | |
| SCHEMBL18413281 | 0.73 | JAK2 (0.81) | JAK1JAK2JAK3TYK2STK10 | |
| SCHEMBL20918456 | 0.72 | JAK1 (0.41) | JAK1ABL1 | |
| SCHEMBL20930347 | 0.72 | JAK1 (0.69) | JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019078619-A1 | HETEROCYCLIC COMPOUND AS A PROTEIN KINASE INHIBITOR | CJ HEALTHCARE CORPORATION (KR) | 2019-04-25 | — | — | WO | disclosed |