SCHEMBL20932686

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30130216	1.00	CYP1A2 (0.45)	CYP1A2CYP2D6HIF1AKMT2AMEN1
	SCHEMBL20920814	0.91	SOS1 (0.39)	CYP1A2CYP2D6HIF1AKMT2AMEN1
	SCHEMBL20920181	0.91	CYP1A2 (0.44)	CYP1A2CYP2D6HIF1AKMT2AMEN1
	SCHEMBL20920834	0.90	CYP1A2 (0.51)	CYP1A2CYP2D6HIF1AKMT2AMEN1
	SCHEMBL22263088	0.82	CYP1A2 (0.42)	CYP1A2CYP2D6HIF1AKMT2AMEN1
	SCHEMBL22275605	0.80	CYP1A2 (0.38)	CYP1A2CYP2D6HIF1AKMT2AMEN1
	SCHEMBL22275736	0.80	CYP1A2 (0.50)	CYP1A2CYP2D6HIF1AKMT2AMEN1
	SCHEMBL20932660	0.79	KMT2A (0.45)	CYP1A2CYP2D6KMT2AMEN1TSHR
	SCHEMBL30130108	0.79	KMT2A (0.45)	CYP1A2CYP2D6KMT2AMEN1TSHR
	SCHEMBL20920185	0.79	CYP1A2 (0.42)	CYP1A2CYP2D6HIF1AKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.