SCHEMBL20933779

SCHEMBL20933779

CC1(C)c2ccccc2-c2c1ccc1c2Oc2cccc(Cl)c2O1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 4/20 0.51
PDK2 Q15119 3/20 0.36
PGR P06401 4/20 0.36
DRD1 P21728 2/20 0.33
ATM Q13315 1/20 0.31
MLNR O43193 1/20 0.30
NR1I2 O75469 1/20 0.30
CHRM2 P08172 1/20 0.30
ADRB1 P08588 1/20 0.30
HTR1A P08908 1/20 0.30
ADRA2A P08913 1/20 0.30
CHRM1 P11229 1/20 0.30
DRD2 P14416 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30
CHRM3 P20309 1/20 0.30
SLC6A2 P23975 1/20 0.30
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30
SLC6A4 P31645 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20934083 0.96 AHR (0.50) AHRPDK2PGRDRD1ATM
SCHEMBL20934246 0.86 AHR (0.38) AHRPGRDRD1ATMMLNR
SCHEMBL20934046 0.81 AHR (0.46) AHRPDK2PGRDRD2HRH1
SCHEMBL20933259 0.81 AHR (0.49) AHRPDK2
SCHEMBL20933258 0.81 AHR (0.46) AHRPDK2PGRDRD2HRH1
SCHEMBL31591201 0.78 PDK2 (0.54) PDK2PGRDRD1MLNRNR1I2
SCHEMBL19849934 0.78 PDK2 (0.54) PDK2PGRDRD1MLNRNR1I2
SCHEMBL20933781 0.78 LPL (0.31) DRD1
SCHEMBL20933688 0.77 AHR (0.47) AHRPDK2ATM
SCHEMBL20933122 0.77 PDK2 (0.33) PDK2DRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019078461-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2019-04-25 WO disclosed