Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TYMP | P19971 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16750127 | 1.00 | LMNA (0.33) | LMNAALDH1A1TDP1TYMPDPP4 | |
| SCHEMBL13691106 | 0.80 | DPP4 (0.32) | DPP4 | |
| SCHEMBL14679340 | 0.80 | DPP4 (0.32) | DPP4 | |
| SCHEMBL5515580 | 0.79 | DPP4 (0.31) | DPP4 | |
| SCHEMBL12112085 | 0.78 | LMNA (0.42) | LMNATDP1DPP4 | |
| SCHEMBL1063255 | 0.77 | LMNA (0.36) | LMNAALDH1A1TYMP | |
| SCHEMBL1712997 | 0.77 | CYP2C19 (0.37) | LMNAALDH1A1TYMP | |
| SCHEMBL10127581 | 0.77 | CA1 (0.41) | ALDH1A1TDP1DPP4PREPFAP | |
| SCHEMBL2746046 | 0.75 | DPP4 (0.53) | DPP4 | |
| SCHEMBL17703490 | 0.74 | LMNA (0.33) | LMNAALDH1A1TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019079373-A1 | PYRIMIDINE TBK/IKKε INHIBITOR COMPOUNDS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2019-04-25 | — | — | WO | disclosed |