SCHEMBL20935176

SCHEMBL20935176

CC(C)C(=O)OCc1ccc(NC(=O)[C@@H](CCCCNC(N)=O)NC(=O)[C@H](NC(=O)CCCCNC(=O)CCl)C(C)C)cc1

nearest known ligand 0.44

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ SIRT2 Q8IXJ6 10/20 0.44
▸ SIRT1 Q96EB6 9/20 0.44
▸ SIRT5 Q9NXA8 6/20 0.43
▸ SIRT3 Q9NTG7 4/20 0.42
▸ FURIN P09958 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24477218 0.98 SIRT2 (0.42) SIRT2SIRT1SIRT5SIRT3FURIN
SCHEMBL25009079 0.98 SIRT2 (0.42) SIRT2SIRT1SIRT5SIRT3FURIN
SCHEMBL19708237 0.94 SIRT2 (0.42) SIRT2SIRT1SIRT5SIRT3FURIN
SCHEMBL20467806 0.94 SIRT2 (0.42) SIRT2SIRT1SIRT5SIRT3FURIN
SCHEMBL19046498 0.92 SIRT2 (0.42) SIRT2SIRT1SIRT5SIRT3FURIN
SCHEMBL17815409 0.92 SIRT2 (0.42) SIRT2SIRT1SIRT5SIRT3FURIN
SCHEMBL19503141 0.92 SIRT2 (0.42) SIRT2SIRT1SIRT5SIRT3FURIN
SCHEMBL17722938 0.92 SIRT2 (0.42) SIRT2SIRT1SIRT5SIRT3FURIN
SCHEMBL20864058 0.91 SIRT2 (0.43) SIRT2SIRT1SIRT5SIRT3FURIN
SCHEMBL21008362 0.91 SIRT2 (0.42) SIRT2SIRT1SIRT5SIRT3FURIN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11161911-B2 Anti-glyco-MUC1 antibodies and their uses GO THERAPEUTICS, INC. (US) 2021-11-02 — — US disclosed
US-20190119400-A1 ANTI-GLYCO-MUC1 ANTIBODIES AND THEIR USES GO THERAPEUTICS, INC. (US) 2019-04-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11161911-B2 Anti-glyco-MUC1 antibodies and their uses MUC1, SIGLEC7, SIGLEC9 SIRT2 3519/4885SIRT1 3972/4885SIRT5 2905/4885
US-20190119400-A1 ANTI-GLYCO-MUC1 ANTIBODIES AND THEIR USES MUC1, SIGLEC7, SIGLEC9 SIRT2 3519/4885SIRT1 3972/4885SIRT5 2905/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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