Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 19/20 | 0.56 |
| ▸ | TDO2 | P48775 | 7/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.49 |
| ▸ | CYP2C8 | P10632 | 3/20 | 0.49 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22274350 | 1.00 | IDO1 (0.56) | IDO1TDO2CYP2C9CYP2C8CHRNA1 | |
| SCHEMBL21289866 | 0.92 | IDO1 (0.54) | IDO1TDO2CYP2C9CYP2C8CHRNA1 | |
| SCHEMBL20919177 | 0.88 | IDO1 (0.62) | IDO1TDO2CYP2C9CYP2C8CHRNA1 | |
| SCHEMBL20935276 | 0.88 | IDO1 (0.62) | IDO1TDO2CYP2C9CYP2C8CHRNA1 | |
| SCHEMBL21289839 | 0.88 | IDO1 (0.51) | IDO1TDO2CYP2C9CYP2C8CHRNA1 | |
| SCHEMBL20935377 | 0.88 | IDO1 (0.50) | IDO1TDO2CYP2C9CYP2C8CHRNA1 | |
| SCHEMBL22274359 | 0.88 | IDO1 (0.56) | IDO1TDO2CYP2C9CYP2C8CHRNA1 | |
| SCHEMBL22274360 | 0.88 | IDO1 (0.56) | IDO1TDO2CYP2C9CYP2C8CHRNA1 | |
| SCHEMBL20935472 | 0.87 | IDO1 (0.56) | IDO1TDO2CYP2C9CYP2C8CHRNA1 | |
| SCHEMBL21289904 | 0.82 | IDO1 (0.65) | IDO1TDO2CYP2C9CYP2C8CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11180497-B2 | Cyclic compounds as immunomodulating agents | ANGEX PHARMACEUTICAL, INC. (US) | 2021-11-23 | — | — | US | disclosed |
| US-20200239464-A1 | CYCLIC COMPOUNDS AS IMMUNOMODULATING AGENTS | ANGEX PHARMACEUTICAL, INC. | 2020-07-30 | — | — | US | disclosed |
| WO-2019078968-A2 | CYCLIC COMPOUNDS AS IMMUNOMODULATING AGENTS | ANGEX PHARMACEUTICAL, INC. (US) | 2019-04-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200239464-A1 | CYCLIC COMPOUNDS AS IMMUNOMODULATING AGENTS | IDO1, IDO2, INMT | IDO1 1/4885TDO2 109/4885CYP2C9 2874/4885 |
| US-11180497-B2 | Cyclic compounds as immunomodulating agents | IDO1, IDO2, INMT | IDO1 1/4885TDO2 65/4885CYP2C9 2445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.