SCHEMBL209362

SCHEMBL209362

C#Cc1c[c]ccc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3610 0.77
Phenylacetylene SCHEMBL5174228 0.75 TSHR (0.42)
SCHEMBL20399742 0.75
SCHEMBL1756357 0.75
SCHEMBL2188836 0.73 APP (0.57)
SCHEMBL6296436 0.72 ALDH1A1 (0.38)
SCHEMBL1978211 0.71
SCHEMBL10736631 0.71 TSHR (0.50)
SCHEMBL27622104 0.70 TSHR (0.42)
Magnesium Chloride Anhydrous SCHEMBL27811650 0.70 TSHR (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 920 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118265702-A Microbiocidal isonicotinamide derivatives 先正达农作物保护股份公司 2024-06-28 CN claimed
WO-2024102177-A1 COMBINATION THERAPIES FOR THE TREATMENT OF BRAIN CANCER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-05-16 WO claimed
US-20240140983-A1 SINGLE STRANDED DNA ENZYME INHIBITORS MASSEY UNIVERSITY (NZ) 2024-05-02 US claimed
CN-117940504-A Triazole containing polymers and methods of use thereof 威廉马什莱斯大学 2024-04-26 CN claimed
WO-2024081447-A1 EGFR INHIBITORS FOR TREATING LUNG CANCER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-04-18 WO claimed
CN-117362200-B Benzenemethylamine compound and synthesis method and application thereof 肇庆学院 2024-04-09 CN claimed
CN-112543781-B Polybenzimidazole oligomers having reactive end groups PBI性能产品公司 2024-02-20 CN claimed
CN-114181222-B Synthesis method and application of azaheterocyclic compound with anti-tumor effect 桂林理工大学 2024-02-06 CN claimed
CN-117362200-A Benzenemethylamine compound and synthesis method and application thereof 肇庆学院 2024-01-09 CN claimed
WO-2023244639-A1 METHODS OF PREDICTING CNS CANCER RESPONSE TO TREATMENT WITH EGFR INHIBITORS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-12-21 WO claimed
US-6376492-B1 GUANIDINE DERIVATIVES MEDIVIR AB (SE) 2002-04-23 US claimed
WO-1999001442-A1 TRIAZINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS ZENECA LIMITED (GB) 1999-01-14 WO claimed
EP-0888351-A1 PYRIMIDO 5,4-D]PYRIMIDINES, MEDICAMENTS CONTAINING THESE COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PRODUCTION Dr. Karl Thomae GmbH (DE) 1999-01-07 EP claimed
US-5849769-A N-arylalkyl-N-heteroarylurea and guandine compounds and methods of treating HIV infection MEDIVIR AB (SE) 1998-12-15 US claimed
EP-0706514-B1 COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES MEDIVIR AB (SE) 1998-11-18 EP claimed
US-5821240-A ENZYME INHIBITORS, SIGNAL INHIBITORS FOR ANTIINFLAMMATORY AGENTS, ANTICARCINOGENIC AGENTS, ANTITUMOR AGENTS AND HORMONE INHIBITORS DR. KARL THOMAE GMBH (DE) 1998-10-13 US claimed
WO-1997032880-A1 PYRIMIDO[5,4-D]PYRIMIDINES, MEDICAMENTS CONTAINING THESE COMPOUNDS, THEIR USE AND PROCESS FOR THEIR PRODUCTION DR. KARL THOMAE GMBH (DE) 1997-09-12 WO claimed
JP-H09502702-A 1997-03-18 JP claimed
EP-0706514-A1 COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES MEDIVIR AB (SE) 1996-04-17 EP claimed
WO-1995006034-A1 COMPOUNDS AND METHODS FOR INHIBITION OF HIV AND RELATED VIRUSES MEDIVIR AB (SE) 1995-03-02 WO claimed