⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20906940 | 0.94 | — | — | |
| SCHEMBL20907054 | 0.88 | — | — | |
| SCHEMBL16158891 | 0.85 | — | — | |
| SCHEMBL13073514 | 0.85 | — | — | |
| SCHEMBL16158896 | 0.85 | — | — | |
| SCHEMBL18884705 | 0.83 | GAA (0.31) | — | |
| SCHEMBL18884704 | 0.83 | GAA (0.31) | — | |
| SCHEMBL18884703 | 0.83 | GAA (0.31) | — | |
| SCHEMBL23711840 | 0.80 | CHRNB2 (0.31) | — | |
| SCHEMBL24759130 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11174250-B2 | Substituted carboxamides as inhibitors of WDR5 protein-protein binding | Propellon Therapeutics Inc. (CA) | 2021-11-16 | — | — | US | disclosed |
| US-20190119264-A1 | INHIBITORS OF WDR5 PROTEIN-PROTEIN BINDING | Propellon Therapeutics Inc. (CA) | 2019-04-25 | — | — | US | disclosed |