Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUCA1 | P04066 | 2/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20937473 | 1.00 | FUCA1 (0.53) | FUCA1SIGMAR1KDM1ADRD2DRD3 | |
| SCHEMBL16041403 | 0.90 | FUCA1 (0.47) | FUCA1SIGMAR1KDM1ADRD2DRD3 | |
| SCHEMBL31382123 | 0.90 | FUCA1 (0.47) | FUCA1SIGMAR1KDM1ADRD2DRD3 | |
| SCHEMBL12372536 | 0.88 | FUCA1 (0.60) | FUCA1SIGMAR1KDM1ADRD2DRD3 | |
| SCHEMBL1021817 | 0.88 | FUCA1 (0.60) | FUCA1SIGMAR1KDM1ADRD2DRD3 | |
| SCHEMBL13783796 | 0.88 | FUCA1 (0.60) | FUCA1SIGMAR1KDM1ADRD2DRD3 | |
| Hydrochloric Acid SCHEMBL15751188 | 0.86 | FUCA1 (0.58) | FUCA1SIGMAR1KDM1ADRD2DRD3 | |
| SCHEMBL4090277 | 0.85 | KDM1A (0.54) | FUCA1SIGMAR1KDM1ADRD2DRD3 | |
| SCHEMBL17304830 | 0.85 | FUCA1 (0.56) | FUCA1SIGMAR1DRD2DRD3S1PR1 | |
| SCHEMBL1088536 | 0.84 | FUCA1 (0.60) | FUCA1SIGMAR1S1PR1S1PR5DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019079783-A1 | ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | VANDERBILT UNIVERSITY (US) | 2019-04-25 | — | — | WO | disclosed |