Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL429692 | 0.80 | LMNA (0.61) | LMNAMAPK1HTTRAB9APDE4A | |
| Hydrochloric Acid SCHEMBL9741360 | 0.79 | PRSS1 (0.59) | LMNAMAPK1HTTRAB9APRSS1 | |
| Hydrochloric Acid SCHEMBL9815151 | 0.78 | LMNA (0.57) | LMNAMAPK1HTTRAB9APDE4A | |
| SCHEMBL30278904 | 0.74 | HTT (0.71) | LMNAMAPK1HTTRAB9AAR | |
| SCHEMBL3668139 | 0.74 | HTT (0.61) | LMNAMAPK1HTTRAB9APDE4A | |
| SCHEMBL1477740 | 0.74 | HTT (0.71) | LMNAMAPK1HTTRAB9AAR | |
| SCHEMBL12324305 | 0.73 | HTT (0.60) | LMNAMAPK1HTTRAB9APDE4A | |
| SCHEMBL2326653 | 0.71 | HTT (0.57) | LMNAMAPK1HTTRAB9APDE4A | |
| SCHEMBL2326651 | 0.71 | RECQL (0.68) | LMNAMAPK1HTTRAB9APDE4A | |
| SCHEMBL2326648 | 0.71 | RECQL (0.68) | LMNAMAPK1HTTRAB9APDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019079783-A1 | ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | VANDERBILT UNIVERSITY (US) | 2019-04-25 | — | — | WO | disclosed |