Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | DAO | P14920 | 1/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6159894 | 0.84 | FLT3 (0.56) | FLT3KDM4EHPGDMAPTDAO | |
| SCHEMBL6470398 | 0.81 | FLT3 (0.58) | FLT3KDM4EHPGDMAPTDAO | |
| SCHEMBL30592039 | 0.79 | FLT3 (0.60) | FLT3KDM4EHPGDMAPTDAO | |
| SCHEMBL8154270 | 0.79 | FLT3 (0.60) | FLT3KDM4EHPGDMAPTDAO | |
| SCHEMBL5653870 | 0.79 | FLT3 (0.64) | FLT3KDM4EHPGDMAPTDAO | |
| SCHEMBL2730199 | 0.79 | IDO1 (0.66) | FLT3KDM4EHPGDMAPTDAO | |
| SCHEMBL6158688 | 0.79 | FLT3 (0.55) | FLT3KDM4EHPGDMAPTDAO | |
| SCHEMBL30148093 | 0.79 | IDO1 (0.66) | FLT3KDM4EHPGDMAPTDAO | |
| SCHEMBL20853214 | 0.78 | HRH4 (0.48) | FLT3HRH4 | |
| SCHEMBL8243662 | 0.77 | KDM4E (0.66) | FLT3KDM4EHPGDMAPTDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3697785-B1 | IMIDAZO-PYRIDINE COMPOUNDS AS PAD INHIBITORS | Jubilant Epipad LLC (US) | 2022-12-28 | — | — | EP | disclosed |
| WO-2019077631-A1 | IMIDAZO-PYRIDINE COMPOUNDS AS PAD INHIBITORS | JUBILANT BIOSYS LIMITED (IN) | 2019-04-25 | — | — | WO | disclosed |