Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | DAO | P14920 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.51 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8243662 | 0.85 | KDM4E (0.66) | FLT3KDM4EDAOMAPTHPGD | |
| SCHEMBL30592039 | 0.83 | FLT3 (0.60) | FLT3KDM4EDAOMAPTHPGD | |
| SCHEMBL8154270 | 0.83 | FLT3 (0.60) | FLT3KDM4EDAOMAPTHPGD | |
| SCHEMBL10898861 | 0.81 | IDO1 (0.52) | FLT3KDM4EDAOMAPTHPGD | |
| SCHEMBL6159894 | 0.80 | FLT3 (0.56) | FLT3KDM4EDAOMAPTHPGD | |
| SCHEMBL5641252 | 0.80 | KDM4E (0.70) | FLT3KDM4EDAOMAPTHPGD | |
| SCHEMBL10176252 | 0.80 | KDM4E (0.50) | FLT3KDM4EDAOMAPTHPGD | |
| SCHEMBL638981 | 0.79 | FLT3 (0.71) | FLT3KDM4EDAOMAPTHPGD | |
| SCHEMBL20937445 | 0.79 | FLT3 (0.55) | FLT3KDM4EDAOMAPTHPGD | |
| SCHEMBL20861119 | 0.79 | FLT3 (0.55) | FLT3KDM4EDAOMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2919998-A1 | COLOUR-FORMING MATERIALS, CONTACT RECORDING DEVICES AND PRESSURE RECORDING DEVICES | Active Device Development Limited (GB) | 2015-09-23 | — | — | EP | claimed |
| WO-2014076468-A1 | COLOUR-FORMING MATERIALS, CONTACT RECORDING DEVICES AND PRESSURE RECORDING DEVICES | ACTIVE DEVICE DEVELOPMENT LIMITED (GB) | 2014-05-22 | — | — | WO | claimed |
| US-5229522-A | Reaction of indole and acetic anhydride with Lewis acids as catalysts | APPLETON PAPERS INC. (US) | 1993-07-20 | — | — | US | claimed |
| US-5116978-A | Vilsmeir reagent | APPLETON PAPERS INC. (US) | 1992-05-26 | — | — | US | claimed |
| EP-0315902-B1 | BIS-INDOLYL ETHYLENE ALDEHYDES | BAYER AG (DE) | 1992-03-18 | — | — | EP | claimed |
| EP-0325708-B1 | BIS-INDOLYL ETHYLENE DERIVATIVES | BAYER AG (DE) | 1992-03-18 | — | — | EP | claimed |
| US-5086171-A | Pressure-sensitive or heat-sensitive mark-forming record systems | APPLETON PAPERS INC. (US) | 1992-02-04 | — | — | US | claimed |
| US-5039821-A | Process for producing di[bis-(indolyl)ethylenyl]tetrahalophthalides | APPLETON PAPERS INC. (US) | 1991-08-13 | — | — | US | claimed |
| US-5001105-A | Bis-(indoly)ethylenes record systems utilizing such compounds | APPLETON PAPERS INC. (US) | 1991-03-19 | — | — | US | claimed |
| US-4996328-A | Chromogens | APPLETON PAPERS INC. (US) | 1991-02-26 | — | — | US | claimed |
| EP-0386992-A2 | Colour formers for recording sheets | APPLETON PAPERS INC. (US) | 1990-09-12 | — | — | EP | claimed |
| US-4931567-A | Bis(indolyl)ethylene compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1990-06-05 | — | — | US | claimed |
| US-4897494-A | REACTING INDOLES WITH CARBOXYLIC ACID IN PRESENCE OF PHOSPHORUS OXYCHLORIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1990-01-30 | — | — | US | claimed |
| EP-0325708-A1 | Bis-indolyl ethylene derivatives | BAYER AG (DE) | 1989-08-02 | — | — | EP | claimed |
| EP-0315902-A1 | Bis-indolyl ethylene aldehydes | BAYER AG (DE) | 1989-05-17 | — | — | EP | claimed |
| JP-3149264-A | — | — | None | — | — | JP | disclosed |
| JP-7150057-A | — | — | None | — | — | JP | disclosed |
| EP-0325708-A1 | Bis-indolyl ethylene derivatives | BAYER AG (DE) | 1989-08-02 | — | — | EP | disclosed |
| EP-0325708-A1 | Bis-indolyl ethylene derivatives | BAYER AG (DE) | 1989-08-02 | — | — | EP | disclosed |
| EP-0325708-A1 | Bis-indolyl ethylene derivatives | BAYER AG (DE) | 1989-08-02 | — | — | EP | disclosed |