Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20943331 | 1.00 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1MAPK1MEN1HPGD | |
| SCHEMBL20943366 | 1.00 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1MAPK1MEN1HPGD | |
| SCHEMBL22465650 | 0.99 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1MAPK1MEN1HPGD | |
| SCHEMBL30018603 | 0.97 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1MAPK1MEN1HPGD | |
| SCHEMBL30019078 | 0.97 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1MAPK1MEN1HPGD | |
| SCHEMBL30019063 | 0.97 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1MAPK1MEN1HPGD | |
| SCHEMBL20943303 | 0.95 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1MAPK1MEN1HPGD | |
| SCHEMBL28531197 | 0.89 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1MAPK1MEN1HPGD | |
| SCHEMBL2228974 | 0.88 | MAPT (0.43) | ALDH1A1L3MBTL1MAPK1MEN1HPGD | |
| SCHEMBL2228971 | 0.88 | MAPT (0.43) | ALDH1A1L3MBTL1MAPK1MEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230286902-A1 | LIPID NANOPARTICLE COMPOSITION | Suzhou Abogen Biosciences Co., Ltd. (CN) | 2023-09-14 | — | — | US | disclosed |
| US-20230286902-A1 | LIPID NANOPARTICLE COMPOSITION | Suzhou Abogen Biosciences Co., Ltd. (CN) | 2023-09-14 | — | — | US | disclosed |
| EP-3476832-B1 | CATIONIC LIPID | EISAI R&D MAN CO LTD (JP) | 2023-04-19 | — | — | EP | disclosed |
| US-11472766-B2 | Lipid nanoparticle composition | Suzhou Abogen Biosciences Co., Ltd. (CN) | 2022-10-18 | — | — | US | disclosed |
| US-20220153686-A1 | LIPID NANOPARTICLE COMPOSITION | Suzhou Abogen Biosciences Co., Ltd. (CN) | 2022-05-19 | — | — | US | disclosed |
| CN-109311809-B | Cationic lipids | 卫材R&D管理有限公司 | 2022-04-08 | — | — | CN | disclosed |
| US-20190218180-A1 | Cationic Lipid | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2019-07-18 | — | — | US | disclosed |
| US-20190218180-A1 | Cationic Lipid | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2019-07-18 | — | — | US | disclosed |
| EP-3476832-A1 | CATIONIC LIPID | Eisai R&D Management Co., Ltd. (JP) | 2019-05-01 | — | — | EP | disclosed |
| EP-3476832-A1 | CATIONIC LIPID | Eisai R&D Management Co., Ltd. (JP) | 2019-05-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190218180-A1 | Cationic Lipid | NPC1L1, NPC1, LPCAT1 | ALDH1A1 1462/4885L3MBTL1 344/4885MAPK1 1519/4885 |
| US-20230286902-A1 | LIPID NANOPARTICLE COMPOSITION | CETP, NPC1, LCAT | ALDH1A1 4587/4885L3MBTL1 1165/4885MAPK1 3444/4885 |
| US-20220153686-A1 | LIPID NANOPARTICLE COMPOSITION | CETP, NPC1, LCAT | ALDH1A1 4587/4885L3MBTL1 1165/4885MAPK1 3444/4885 |
| US-11472766-B2 | Lipid nanoparticle composition | CETP, NPC1, LCAT | ALDH1A1 4587/4885L3MBTL1 1165/4885MAPK1 3444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.