Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | BTN3A1 | O00481 | 7/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26275787 | 1.00 | POLRMT (0.41) | POLRMTCYP3A4CYP2C9BTN3A1 | |
| SCHEMBL16708552 | 1.00 | POLRMT (0.41) | POLRMTCYP3A4CYP2C9BTN3A1 | |
| SCHEMBL26275827 | 0.95 | POLRMT (0.40) | POLRMTCYP3A4CYP2C9BTN3A1 | |
| SCHEMBL26275829 | 0.95 | POLRMT (0.40) | POLRMTCYP3A4CYP2C9BTN3A1 | |
| SCHEMBL26275831 | 0.95 | POLRMT (0.40) | POLRMTCYP3A4CYP2C9BTN3A1 | |
| SCHEMBL23818613 | 0.95 | POLRMT (0.42) | POLRMTCYP3A4CYP2C9BTN3A1 | |
| SCHEMBL27228074 | 0.95 | POLRMT (0.42) | POLRMTCYP3A4CYP2C9BTN3A1 | |
| SCHEMBL27232088 | 0.95 | POLRMT (0.42) | POLRMTCYP3A4CYP2C9BTN3A1 | |
| SCHEMBL26275836 | 0.95 | POLRMT (0.42) | POLRMTCYP3A4CYP2C9BTN3A1 | |
| SCHEMBL27232620 | 0.95 | POLRMT (0.42) | POLRMTCYP3A4CYP2C9BTN3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068405-B1 | PYRROLO [1,2,F][1,2,4]TRIAZINES USEFUL FOR TREATING RESPIRATORY SYNCITIAL VIRUS INFECTIONS | GILEAD SCIENCES INC (US) | 2019-05-01 | — | — | EP | disclosed |