SCHEMBL20945430

SCHEMBL20945430

Cc1cccc(-c2ccc(Nc3ccc(N(c4ccc(Nc5ccc(-c6cccc(C)c6)cc5)cc4)c4ccc(Nc5ccc(-c6cccc(C)c6)cc5)cc4)cc3)cc2)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 1/20 0.48
HSD17B2 P37059 1/20 0.48
NPSR1 Q6W5P4 1/20 0.47
FNTA P49354 1/20 0.46
FNTB P49356 1/20 0.46
ENPP3 O14638 1/20 0.41
CNR1 P21554 1/20 0.40
CSF1R P07333 1/20 0.40
FLT1 P17948 1/20 0.40
FLT3 P36888 1/20 0.40
HPGD P15428 1/20 0.38
BRD4 O60885 1/20 0.38
CREBBP Q92793 1/20 0.38
PGR P06401 1/20 0.38
PNPLA2 Q96AD5 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.37
GAA P10253 1/20 0.37
MAPKAPK2 P49137 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1370873 0.95 NPSR1 (0.51) HSD17B1HSD17B2NPSR1FNTAFNTB
SCHEMBL4897188 0.92 NPSR1 (0.55) HSD17B1HSD17B2NPSR1FNTAFNTB
SCHEMBL19473599 0.89 NPSR1 (0.57) HSD17B1HSD17B2NPSR1FNTAFNTB
SCHEMBL17678537 0.89 HSD17B1 (0.51) HSD17B1HSD17B2FNTAFNTBENPP3
SCHEMBL13175100 0.89 NPSR1 (0.66) NPSR1CSF1RFLT1FLT3HPGD
SCHEMBL12955702 0.87 NPSR1 (0.64) HSD17B1HSD17B2NPSR1CSF1RFLT1
SCHEMBL20817036 0.87 HPGD (0.48) HSD17B1HSD17B2NPSR1HPGDPNPLA2
SCHEMBL29359258 0.87 NPSR1 (0.53) HSD17B1HSD17B2NPSR1HPGDKMT2A
SCHEMBL14549384 0.86 NPSR1 (0.62) NPSR1CSF1RFLT1FLT3HPGD
SCHEMBL21705016 0.85 NPSR1 (0.64) HSD17B1HSD17B2NPSR1FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11653512-B2 Light-emitting diode and light-emitting device with reduced hole and current leakages LG DISPLAY CO., LTD. (KR) 2023-05-16 US disclosed
US-20190131557-A1 LIGHT-EMITTING DIODE AND LIGHT-EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2019-05-02 US disclosed