Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 2/20 | 0.52 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.47 |
| ▸ | TLR9 | Q9NR96 | 5/20 | 0.47 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.47 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.47 |
| ▸ | EPHA2 | P29317 | 5/20 | 0.47 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
| ▸ | KMT5A | Q9NQR1 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | PGK1 | P00558 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5016778 | 0.86 | NSD2 (0.49) | NSD2EHMT2KDM1ARCOR1TLR9 | |
| SCHEMBL18788125 | 0.84 | DNMT1 (0.57) | EHMT2DNMT3A | |
| SCHEMBL17179600 | 0.84 | EPHA2 (0.52) | NSD2EPHA2EPHB4KDRERBB2 | |
| SCHEMBL664787 | 0.84 | EPHA2 (0.52) | NSD2EPHA2EPHB4KDRERBB2 | |
| SCHEMBL20951515 | 0.82 | KDR (0.55) | EHMT2KDR | |
| SCHEMBL5828984 | 0.80 | EPHA2 (0.50) | NSD2EHMT2KDM1ARCOR1TLR9 | |
| SCHEMBL19260615 | 0.80 | TLR9 (0.49) | NSD2EHMT2KDM1ARCOR1TLR9 | |
| SCHEMBL3132645 | 0.80 | EPHA2 (0.55) | NSD2EPHA2EPHB4KDRERBB2 | |
| SCHEMBL5622929 | 0.80 | NSD2 (0.48) | NSD2EHMT2KDM1ARCOR1TLR9 | |
| SCHEMBL24010104 | 0.79 | PIK3CD (0.55) | NSD2EHMT2KDM1ARCOR1DNMT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190127354-A1 | 2,4,6,7-TETRASUBSTITUTED QUINOLINE COMPOUNDS AS INHIBITORS OF DNA METHYLTRANSFERASES | FUNDACIÓN PARA LA INVESTIGACIÓN MÉDICA APLICADA (ES) | 2019-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190127354-A1 | 2,4,6,7-TETRASUBSTITUTED QUINOLINE COMPOUNDS AS INHIBITORS OF DNA METHYLTRANSFERASES | DNMT3B, DNMT1, DNMT3A | NSD2 86/4885EHMT2 20/4885KDM1A 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.