Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 10/20 | 0.56 |
| ▸ | CCND1 | P24385 | 10/20 | 0.56 |
| ▸ | CCNE2 | O96020 | 7/20 | 0.56 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.56 |
| ▸ | CDK2 | P24941 | 7/20 | 0.56 |
| ▸ | CAMK2B | Q13554 | 5/20 | 0.56 |
| ▸ | CAMK2G | Q13555 | 5/20 | 0.56 |
| ▸ | CAMK2D | Q13557 | 5/20 | 0.56 |
| ▸ | CAMK2A | Q9UQM7 | 5/20 | 0.56 |
| ▸ | CCNB2 | O95067 | 5/20 | 0.56 |
| ▸ | CDK1 | P06493 | 5/20 | 0.56 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.56 |
| ▸ | CCNB3 | Q8WWL7 | 5/20 | 0.56 |
| ▸ | PRKACA | P17612 | 2/20 | 0.56 |
| ▸ | PRKACG | P22612 | 2/20 | 0.56 |
| ▸ | PRKACB | P22694 | 2/20 | 0.56 |
| ▸ | PARP1 | P09874 | 4/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.50 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.50 |
| ▸ | PRKCG | P05129 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL20954044 | 0.83 | CDK4 (0.49) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL28823926 | 0.81 | CDK4 (0.57) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL31613098 | 0.81 | CDK4 (0.57) | CDK4CCND1CCNE2CCNE1CDK2 | |
| Biphenyl SCHEMBL20954051 | 0.80 | CDK4 (0.51) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL31613100 | 0.73 | PARP1 (0.53) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL30300692 | 0.72 | CDK4 (0.42) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL31091073 | 0.72 | MAPK1 (0.47) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL29516962 | 0.70 | PARP1 (1.00) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL27986237 | 0.70 | HPGD (0.45) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL5381581 | 0.70 | PARP1 (1.00) | CDK4CCND1CCNE2CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3279193-B1 | COMPOUNDS COMPRISING A PHTHALIMIDE GROUP AND CARBAZOLE OR ITS ANALOGUES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2019-05-08 | — | — | EP | disclosed |