Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 12/20 | 0.49 |
| ▸ | CCND1 | P24385 | 12/20 | 0.49 |
| ▸ | CCNE2 | O96020 | 9/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 9/20 | 0.49 |
| ▸ | CDK2 | P24941 | 9/20 | 0.49 |
| ▸ | CAMK2B | Q13554 | 7/20 | 0.49 |
| ▸ | CAMK2G | Q13555 | 7/20 | 0.49 |
| ▸ | CAMK2D | Q13557 | 7/20 | 0.49 |
| ▸ | CAMK2A | Q9UQM7 | 7/20 | 0.49 |
| ▸ | CCNB2 | O95067 | 5/20 | 0.49 |
| ▸ | CDK1 | P06493 | 5/20 | 0.49 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.49 |
| ▸ | CCNB3 | Q8WWL7 | 5/20 | 0.49 |
| ▸ | PRKACA | P17612 | 2/20 | 0.49 |
| ▸ | PRKACG | P22612 | 2/20 | 0.49 |
| ▸ | PRKACB | P22694 | 2/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL20954057 | 0.83 | CDK4 (0.56) | CDK4CCND1CCNE2CCNE1CDK2 | |
| Biphenyl SCHEMBL20954051 | 0.82 | CDK4 (0.51) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL31613098 | 0.80 | CDK4 (0.57) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL28823926 | 0.80 | CDK4 (0.57) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL1683250 | 0.78 | ESR1 (0.55) | MEN1MAPTKMT2AMAOA | |
| SCHEMBL31091078 | 0.72 | MAPK1 (0.46) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL31091094 | 0.72 | GABRP (0.45) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL31613100 | 0.72 | PARP1 (0.53) | CDK4CCND1CCNE2CCNE1CDK2 | |
| SCHEMBL3270153 | 0.72 | MAOA (0.46) | CDK4CCND1MAOA | |
| SCHEMBL30022347 | 0.72 | ESR1 (0.46) | CDK4CCND1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3279193-B1 | COMPOUNDS COMPRISING A PHTHALIMIDE GROUP AND CARBAZOLE OR ITS ANALOGUES FOR USE IN ORGANIC OPTOELECTRONIC DEVICES | CYNORA GMBH (DE) | 2019-05-08 | — | — | EP | disclosed |