Edetic Acid

Edetic Acid

SCHEMBL20955

O=C(O)CN(CCN(CC(=O)O)CC(=O)O)CC(=O)O.OB(O)O

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.82
EYA2 O00167 1/20 0.82
APP P05067 1/20 0.82
ACE P12821 1/20 0.82
BLM P54132 2/20 0.78
PMP22 Q01453 2/20 0.78
KDM4E B2RXH2 2/20 0.78
ALOX15 P16050 2/20 0.78
TSHR P16473 2/20 0.78
LMNA P02545 1/20 0.78
CHRM2 P08172 1/20 0.78
ADRA2A P08913 1/20 0.78
DRD1 P21728 1/20 0.78
SLC6A2 P23975 1/20 0.78
SLC6A4 P31645 1/20 0.78
CYP2C19 P33261 1/20 0.78
ADRA1A P35348 1/20 0.78
DRD3 P35462 1/20 0.78
SLC6A3 Q01959 1/20 0.78
HRH3 Q9Y5N1 1/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Edetic Acid SCHEMBL68140 1.00 TDP1 (0.82) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL6684859 0.92 TDP1 (0.70) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL1373 0.91 TDP1 (1.00) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL8607480 0.91 TDP1 (1.00) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL16714076 0.91 TDP1 (1.00) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL3035039 0.91 TDP1 (1.00) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL8624198 0.91 TDP1 (1.00) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL15136 0.91 TDP1 (1.00) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL16570043 0.90 TDP1 (0.67) TDP1EYA2APPACEBLM
Edetic Acid SCHEMBL10542859 0.88 TDP1 (0.93) TDP1EYA2APPACEBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240181223-A1 NEUROSURGICAL APPARATUS AND METHODS RENISHAW PLC (GB) 2024-06-06 US disclosed
EP-2877108-B1 NEUROSURGICAL APPARATUS RENISHAW PLC (GB) 2023-06-07 EP disclosed
EP-3830182-A1 HIGH-MOLECULAR-WEIGHT FUCANS FOR TREATING FIBROUS ADHESIONS AND OTHER DISEASES AND CONDITIONS Arc Medical Devices, Inc. (CA) 2021-06-09 EP disclosed
US-20200324089-A1 NEUROSURGICAL APPARATUS AND METHODS RENISHAW PLC (GB) 2020-10-15 US disclosed
US-10751513-B2 Neurosurgical apparatus and methods RENISHAW PLC (GB) 2020-08-25 US disclosed
WO-2020019078-A1 HIGH-MOLECULAR-WEIGHT FUCANS FOR TREATING FIBROUS ADHESIONS AND OTHER DISEASES AND CONDITIONS ARC MEDICAL DEVICES INC. (CA) 2020-01-30 WO disclosed
CN-105377302-B Polymer micelle medical composition 那野伽利阿株式会社 2018-05-11 CN disclosed
CN-101952461-B For detecting composition, method and the kit of ribonucleic acid 应用生物系统有限公司 2017-12-05 CN disclosed
US-20160114058-A1 POLYMER MICELLE PHARMACEUTICAL COMPOSITION NANOCARRIER CO., LTD. (JP) 2016-04-28 US disclosed
EP-2997979-A1 POLYMERIC MICELLE PHARMACEUTICAL COMPOSITION NanoCarrier Co., Ltd. (JP) 2016-03-23 EP disclosed
EP-0794953-A1 QUINAZOLINE DERIVATIVES ZENECA LIMITED (GB) 1997-09-17 EP disclosed
EP-0737085-A1 VACCINE FOR $i(BRANHAMELLA CATARRHALIS) THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK AT BUFFALO (US) 1996-10-16 EP disclosed
WO-1996016960-A1 QUINAZOLINE DERIVATIVES ZENECA LIMITED (GB) 1996-06-06 WO disclosed
WO-1995009025-A1 VACCINE FOR $i(BRANHAMELLA CATARRHALIS) THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 1995-04-06 WO disclosed
US-5219739-A Wound healing agents SCIOS NOVA INC. (US) 1993-06-15 US disclosed
US-5194596-A Wound healing agents CALIFORNIA BIOTECHNOLOGY INC. (US) 1993-03-16 US disclosed
EP-0514501-A1 DETECTION OF POINT MUTATIONS IN GENES ENCODING GTP BINDING PROTEINS F. HOFFMANN-LA ROCHE AG (CH) 1992-11-25 EP disclosed
WO-1991012343-A2 DETECTION OF POINT MUTATIONS IN GENES ENCODING GTP BINDING PROTEINS F. HOFFMANN-LA ROCHE AG (CH) 1991-08-22 WO disclosed
US-4159895-A MEAN CORPUSCULAR VOLUME AND MEAN CORPUSCULAR HEMOGLOBIN COULTER ELECTRONICS, INC. (US) 1979-07-03 US disclosed
US-3955928-A Pregnancy test YEE HUGH 1976-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160114058-A1 POLYMER MICELLE PHARMACEUTICAL COMPOSITION SSR4, ABCC1, PMM2 TDP1 3436/4885EYA2 4307/4885APP 7/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.