Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19857322 | 0.79 | HTT (0.40) | HTTMERTK | |
| SCHEMBL19857380 | 0.79 | HTT (0.40) | HTTMERTK | |
| SCHEMBL29507789 | 0.79 | HTT (0.40) | HTTMERTK | |
| SCHEMBL29594214 | 0.79 | HTT (0.40) | HTTMERTK | |
| SCHEMBL29798910 | 0.77 | HTT (0.39) | HTTMERTK | |
| SCHEMBL19863579 | 0.77 | HTT (0.39) | HTTMERTK | |
| SCHEMBL29595384 | 0.77 | HTT (0.39) | HTTMERTK | |
| SCHEMBL4715006 | 0.75 | MERTK (0.50) | HTTMERTK | |
| SCHEMBL22860424 | 0.74 | HTT (0.40) | HTTMERTK | |
| SCHEMBL22860693 | 0.73 | MERTK (0.46) | HTTMERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10800783-B2 | CDK2/4/6 inhibitors | PFIZER INC. (US) | 2020-10-13 | — | — | US | disclosed |
| US-20190135817-A1 | CDK2/4/6 Inhibitors | PFIZER INC. (US) | 2019-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10800783-B2 | CDK2/4/6 inhibitors | CDK2, CDK6, CDK20 | HTT 3428/4885MERTK 3203/4885 |
| US-20190135817-A1 | CDK2/4/6 Inhibitors | CDK2, CDK6, CDK20 | HTT 3428/4885MERTK 3203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.