Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | MERTK | Q12866 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19863579 | 1.00 | HTT (0.39) | HTTNR3C1PGRARMERTK | |
| SCHEMBL29798910 | 1.00 | HTT (0.39) | HTTNR3C1PGRARMERTK | |
| SCHEMBL19857322 | 0.81 | HTT (0.40) | HTTNR3C1PGRARMERTK | |
| SCHEMBL29507789 | 0.81 | HTT (0.40) | HTTNR3C1PGRARMERTK | |
| SCHEMBL29594214 | 0.81 | HTT (0.40) | HTTNR3C1PGRARMERTK | |
| SCHEMBL19857380 | 0.81 | HTT (0.40) | HTTNR3C1PGRARMERTK | |
| SCHEMBL20955932 | 0.81 | NR3C1 (0.36) | NR3C1PGRARTYK2ALDH1A1 | |
| SCHEMBL20955933 | 0.81 | NR3C1 (0.36) | NR3C1PGRARTYK2ALDH1A1 | |
| SCHEMBL19863577 | 0.78 | ALDH1A1 (0.53) | HTTALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL20955940 | 0.77 | HTT (0.39) | HTTMERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114394966-A | Pyridopyrimidinone CDK2/4/6 inhibitors | 辉瑞公司 | 2022-04-26 | — | — | CN | disclosed |