Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15667395 | 0.82 | MAOA (0.46) | PARP1MAOAKDM4EALDH1A1TSHR | |
| SCHEMBL15666675 | 0.82 | MAOA (0.46) | PARP1MAOAKDM4EALDH1A1TSHR | |
| SCHEMBL15666673 | 0.82 | MAOA (0.46) | PARP1MAOAKDM4EALDH1A1TSHR | |
| SCHEMBL24074379 | 0.73 | PARP1 (0.40) | PARP1MAOAKDM4EALDH1A1TSHR | |
| SCHEMBL1285589 | 0.71 | PARP1 (0.58) | PARP1MAOAKDM4EALDH1A1TSHR | |
| SCHEMBL18181796 | 0.71 | PARP1 (0.50) | PARP1MAOAKDM4EALDH1A1TSHR | |
| SCHEMBL27217655 | 0.71 | PARP1 (0.50) | PARP1MAOAKDM4EALDH1A1TSHR | |
| SCHEMBL10830763 | 0.69 | MAOA (0.46) | PARP1MAOAKDM4EALDH1A1TSHR | |
| SCHEMBL20958083 | 0.68 | PARP1 (0.60) | PARP1MAOAALDH1A1 | |
| SCHEMBL29661388 | 0.68 | HTR2A (0.37) | PARP1KDM1AKDM1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3476848-A1 | BENZOFURAN PYRAZOLE AMINE PROTEIN KINASE INHIBITOR | Hangzhou Rex Pharmaceutical Co., Ltd (CN) | 2019-05-01 | — | — | EP | disclosed |