⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14236594 | 0.82 | NCF1 (0.31) | — | |
| SCHEMBL18901501 | 0.70 | — | — | |
| SCHEMBL25055378 | 0.70 | — | — | |
| SCHEMBL22946672 | 0.68 | — | — | |
| SCHEMBL19262269 | 0.67 | — | — | |
| SCHEMBL21258523 | 0.67 | NCF1 (0.30) | — | |
| SCHEMBL14067485 | 0.67 | NCF1 (0.30) | — | |
| SCHEMBL19734188 | 0.67 | NCF1 (0.30) | — | |
| SCHEMBL19734185 | 0.67 | NCF1 (0.30) | — | |
| SCHEMBL12424297 | 0.67 | NCF1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3476848-A1 | BENZOFURAN PYRAZOLE AMINE PROTEIN KINASE INHIBITOR | Hangzhou Rex Pharmaceutical Co., Ltd (CN) | 2019-05-01 | — | — | EP | disclosed |