Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | PI4KA | P42356 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7460963 | 0.84 | MAPT (0.41) | NOTUMALDH1A1HPGDKMT2AHSD17B10 | |
| SCHEMBL11926858 | 0.83 | CYP2A6 (0.62) | ALDH1A1CYP2A6CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL2095967 | 0.83 | CYP2A6 (0.50) | NOTUMALDH1A1HPGDKMT2AHSD17B10 | |
| SCHEMBL2095209 | 0.80 | CYP1A2 (0.63) | ALDH1A1HPGDCYP2A6MAOBMAOA | |
| SCHEMBL9454459 | 0.79 | CYP2A6 (0.53) | ALDH1A1KMT2AHSD17B10CYP2A6CYP1A2 | |
| SCHEMBL13666136 | 0.79 | CYP2C9 (0.74) | ALDH1A1KMT2ACYP2A6CYP1A2CYP2D6 | |
| SCHEMBL21893497 | 0.78 | CYP1A2 (0.45) | ALDH1A1HPGDKMT2AHSD17B10CYP2A6 | |
| SCHEMBL2356727 | 0.77 | CYP1A2 (0.44) | ALDH1A1HPGDKMT2AHSD17B10CYP2A6 | |
| SCHEMBL29891238 | 0.77 | CYP1A2 (0.44) | ALDH1A1HPGDKMT2AHSD17B10CYP2A6 | |
| SCHEMBL30038775 | 0.77 | CYP1A2 (0.44) | ALDH1A1HPGDKMT2AHSD17B10CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163753-B2 | 2-(4-(4-(4-chlorophenyl)oxazol-2-yl)phenoxymethyl)-2-methyl-6-nitro-2,3-dihydroimidazo[2,1-b]oxazole; bactericide; excellent bactericidal action against Mycobacterium tuberculosis, multi-drug-resistant Mycobacterium tuberculosis, and atypical acid-fast bacteria | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-04-24 | — | — | US | disclosed |
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |
| US-20080119478-A1 | 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis | OTSUKA PHAMACEUTICAL CO., LTD. (JP) | 2008-05-22 | — | — | US | disclosed |
| EP-1171484-A1 | PROCESS FOR PRODUCING POLYOLEFINS | EASTMAN CHEMICAL COMPANY (US) | 2002-01-16 | — | — | EP | disclosed |
| EP-1171485-A1 | PROCESS FOR PRODUCING POLYOLEFINS | EASTMAN CHEMICAL COMPANY (US) | 2002-01-16 | — | — | EP | disclosed |
| WO-2000058372-A1 | PROCESS FOR PRODUCING POLYOLEFINS | EASTMAN CHEMICAL COMPANY (US) | 2000-10-05 | — | — | WO | disclosed |
| WO-2000058371-A1 | PROCESS FOR PRODUCING POLYOLEFINS | EASTMAN CHEMICAL COMPANY (US) | 2000-10-05 | — | — | WO | disclosed |
| EP-0986544-A1 | DIPHENYL-TRIAZOLE DERIVATIVES AND THEIR USE AS ANTI-GESTATIVE, IMMUNO-SUPPRESSANT AND ANTI-TUMORAL AGENTS | Geange Ltd. (IE) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998055463-A1 | DIPHENYL-TRIAZOLE DERIVATIVES AND THEIR USE AS ANTI-GESTATIVE, IMMUNO-SUPPRESSANT AND ANTI-TUMORAL AGENTS | GEANGE LTD. (IE) | 1998-12-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119478-A1 | 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis | NR2C2, NR0B2, NR4A2 | NOTUM 4043/4885ALDH1A1 412/4885HPGD 1951/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.