Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.56 |
| ▸ | TDO2 | P48775 | 2/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | JUN | P05412 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8486922 | 0.83 | NAPRT (0.48) | NPC1RAB9AMEN1KMT2AGRM4 | |
| SCHEMBL8486928 | 0.83 | NAPRT (0.48) | NPC1RAB9AMEN1KMT2AGRM4 | |
| SCHEMBL28763149 | 0.79 | NPC1 (0.57) | NPC1RAB9AMEN1KMT2ACYP11B1 | |
| SCHEMBL29694393 | 0.79 | NPC1 (0.57) | NPC1RAB9AMEN1KMT2ACYP11B1 | |
| SCHEMBL29691639 | 0.79 | CYP11B1 (0.86) | NPC1RAB9AMEN1KMT2ACYP11B1 | |
| SCHEMBL29691623 | 0.79 | CYP11B1 (0.86) | NPC1RAB9AMEN1KMT2ACYP11B1 | |
| SCHEMBL29691532 | 0.77 | CYP11B1 (0.82) | NPC1RAB9AMEN1KMT2ACYP11B1 | |
| SCHEMBL29691514 | 0.77 | CYP11B1 (0.82) | NPC1RAB9AMEN1KMT2ACYP11B1 | |
| SCHEMBL29691548 | 0.77 | CYP11B1 (0.82) | NPC1RAB9AMEN1KMT2ACYP11B1 | |
| SCHEMBL29691464 | 0.77 | CYP11B1 (0.82) | NPC1RAB9AMEN1KMT2ACYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3229288-B1 | POLYMER, AND MIXTURE, FORMULATION AND ORGANIC ELECTRONIC DEVICE CONTAINING THE SAME, AND MONOMER THEREOF | GUANGZHOU CHINARAY OPTOELECTRONIC MAT LTD (CN) | 2019-05-01 | — | — | EP | disclosed |