Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.59 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.34 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.34 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 7/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 6/20 | 0.33 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.32 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.32 |
| ▸ | RNASEL | Q05823 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19101797 | 0.80 | POLRMT (0.64) | POLRMTP2RY2P2RY1P2RY11P2RX3 | |
| SCHEMBL16699126 | 0.79 | POLRMT (0.64) | POLRMTP2RY2P2RY1P2RY11P2RX3 | |
| SCHEMBL16698889 | 0.79 | POLRMT (0.61) | POLRMTP2RY2P2RY1P2RY11P2RX3 | |
| SCHEMBL20756290 | 0.78 | POLRMT (0.73) | POLRMTP2RY2P2RY1P2RY11P2RX3 | |
| SCHEMBL16698743 | 0.78 | POLRMT (0.62) | POLRMTP2RY2P2RY1P2RY11P2RX3 | |
| SCHEMBL24942350 | 0.78 | POLRMT (0.64) | POLRMTP2RY2P2RY1P2RY11P2RX3 | |
| SCHEMBL23827914 | 0.78 | POLRMT (0.70) | POLRMTP2RY2P2RY1P2RY11P2RX3 | |
| SCHEMBL16708503 | 0.77 | POLRMT (0.61) | POLRMTP2RY2P2RY1P2RY11P2RX3 | |
| SCHEMBL16708510 | 0.77 | POLRMT (0.61) | POLRMTP2RY2P2RY1P2RY11P2RX3 | |
| SCHEMBL20755989 | 0.77 | POLRMT (0.72) | POLRMTP2RY2P2RY1P2RY11P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068405-B1 | PYRROLO [1,2,F][1,2,4]TRIAZINES USEFUL FOR TREATING RESPIRATORY SYNCITIAL VIRUS INFECTIONS | GILEAD SCIENCES INC (US) | 2019-05-01 | — | — | EP | disclosed |