Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 8/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 6/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | MERTK | Q12866 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19101788 | 0.88 | TNK2 (0.38) | TNK2RIPK1 | |
| SCHEMBL23818461 | 0.86 | TNK2 (0.34) | TNK2RIPK1 | |
| SCHEMBL25853408 | 0.86 | TNK2 (0.34) | TNK2RIPK1 | |
| SCHEMBL18371668 | 0.86 | TNK2 (0.38) | TNK2RIPK1 | |
| SCHEMBL16708501 | 0.86 | TNK2 (0.38) | TNK2RIPK1 | |
| SCHEMBL25852186 | 0.85 | TNK2 (0.35) | TNK2RIPK1NTRK1NTRK2 | |
| SCHEMBL25852255 | 0.85 | TNK2 (0.35) | TNK2RIPK1NTRK1NTRK2 | |
| SCHEMBL18371662 | 0.83 | TNK2 (0.35) | TNK2RIPK1NTRK1NTRK2 | |
| SCHEMBL10120675 | 0.83 | TNK2 (0.35) | TNK2RIPK1NTRK1NTRK2 | |
| SCHEMBL10120838 | 0.83 | TNK2 (0.35) | TNK2RIPK1NTRK1NTRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068405-B1 | PYRROLO [1,2,F][1,2,4]TRIAZINES USEFUL FOR TREATING RESPIRATORY SYNCITIAL VIRUS INFECTIONS | GILEAD SCIENCES INC (US) | 2019-05-01 | — | — | EP | disclosed |