Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 5/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 6/20 | 0.33 |
| ▸ | POLRMT | O00411 | 1/20 | 0.31 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25853408 | 1.00 | TNK2 (0.34) | TNK2RIPK1POLRMTHSPA5 | |
| SCHEMBL22372328 | 0.94 | TNK2 (0.32) | TNK2RIPK1 | |
| SCHEMBL19101788 | 0.90 | TNK2 (0.38) | TNK2RIPK1HSPA5 | |
| SCHEMBL24736751 | 0.89 | TNK2 (0.32) | TNK2RIPK1POLRMT | |
| SCHEMBL20756552 | 0.87 | TNK2 (0.33) | TNK2RIPK1 | |
| SCHEMBL19101809 | 0.87 | TNK2 (0.33) | TNK2RIPK1 | |
| SCHEMBL20960001 | 0.86 | TNK2 (0.38) | TNK2RIPK1 | |
| SCHEMBL25852186 | 0.85 | TNK2 (0.35) | TNK2RIPK1 | |
| SCHEMBL25852255 | 0.85 | TNK2 (0.35) | TNK2RIPK1 | |
| SCHEMBL31725287 | 0.82 | PDE2A (0.38) | TNK2RIPK1HSPA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4323362-B1 | METHODS OF PREPARING CARBANUCLEOSIDES USING AMIDES | GILEAD SCIENCES INC (US) | 2025-05-07 | — | — | EP | disclosed |
| EP-4323362-A1 | METHODS OF PREPARING CARBANUCLEOSIDES USING AMIDES | GILEAD SCIENCES, INC. (US) | 2024-02-21 | — | — | EP | disclosed |
| US-11697666-B2 | Methods of preparing carbanucleosides using amides | GILEAD SCIENCES, INC. (US) | 2023-07-11 | — | — | US | disclosed |
| US-11697666-B2 | Methods of preparing carbanucleosides using amides | GILEAD SCIENCES, INC. (US) | 2023-07-11 | — | — | US | disclosed |
| US-20220372057-A1 | METHODS OF PREPARING CARBANUCLEOSIDES USING AMIDES | GILEAD SCIENCES, INC. | 2022-11-24 | — | — | US | disclosed |
| WO-2022221514-A1 | METHODS OF PREPARING CARBANUCLEOSIDES USING AMIDES | GILEAD SCIENCES, INC. (US) | 2022-10-20 | — | — | WO | disclosed |
| US-20210284669-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2021-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11697666-B2 | Methods of preparing carbanucleosides using amides | NCL, DUT, POLN | TNK2 732/4885RIPK1 3841/4885POLRMT 89/4885 |
| US-20210284669-A1 | ANTIVIRAL COMPOUNDS | MAVS, HAVCR2, SNRPA | TNK2 4626/4885RIPK1 722/4885POLRMT 352/4885 |
| US-20220372057-A1 | METHODS OF PREPARING CARBANUCLEOSIDES USING AMIDES | NCL, DUT, POLN | TNK2 732/4885RIPK1 3841/4885POLRMT 89/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.