⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20960152 | 0.90 | — | — | |
| SCHEMBL19101813 | 0.86 | — | — | |
| SCHEMBL20756370 | 0.85 | — | — | |
| SCHEMBL20960069 | 0.77 | — | — | |
| SCHEMBL16708590 | 0.76 | PNP (0.33) | — | |
| SCHEMBL18379740 | 0.76 | PNP (0.33) | — | |
| SCHEMBL20943584 | 0.76 | PNP (0.33) | — | |
| SCHEMBL16698792 | 0.75 | POLRMT (0.41) | — | |
| SCHEMBL20756115 | 0.75 | POLRMT (0.41) | — | |
| SCHEMBL807421 | 0.75 | HIF1A (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3068405-B1 | PYRROLO [1,2,F][1,2,4]TRIAZINES USEFUL FOR TREATING RESPIRATORY SYNCITIAL VIRUS INFECTIONS | GILEAD SCIENCES INC (US) | 2019-05-01 | — | — | EP | disclosed |