Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | WRN | Q14191 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22538847 | 0.84 | PTGS1 (0.39) | ALDH1A1BLMGMNNLMNAMAPT | |
| SCHEMBL15386866 | 0.82 | KMT2A (0.56) | KMT2AMEN1GSK3AGSK3BALDH1A1 | |
| SCHEMBL29633571 | 0.79 | PTGS1 (0.53) | KMT2AMEN1ALDH1A1LMNAMAPT | |
| SCHEMBL14463606 | 0.78 | PTGS1 (0.35) | ALDH1A1LMNAMAPTNPSR1MGLL | |
| SCHEMBL20436166 | 0.76 | PTGS1 (0.39) | ALDH1A1LMNAMAPTNPSR1MGLL | |
| SCHEMBL21276451 | 0.76 | PTGS1 (0.39) | ALDH1A1LMNAMAPTNPSR1MGLL | |
| SCHEMBL30661207 | 0.75 | FNTA (0.45) | KMT2AMEN1GSK3AGSK3BALDH1A1 | |
| SCHEMBL22311926 | 0.74 | MME (0.42) | KMT2AMEN1GSK3AGSK3BALDH1A1 | |
| SCHEMBL18342493 | 0.74 | KMT2A (0.40) | KMT2AMEN1GSK3AGSK3BALDH1A1 | |
| SCHEMBL23071907 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2961435-B1 | CONJUGATES COMPRISING CELL-BINDING AGENTS AND CYTOTOXIC AGENTS | IMMUNOGEN INC (US) | 2019-05-01 | — | — | EP | disclosed |