Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.80 |
| ▸ | FABP4 | P15090 | 3/20 | 0.75 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.75 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.69 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.69 |
| ▸ | FABP3 | P05413 | 1/20 | 0.61 |
| ▸ | MAOA | P21397 | 4/20 | 0.50 |
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | FNTA | P49354 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20961100 | 0.98 | KDM4E (0.77) | KDM4EFABP4FABP5HDAC6HDAC1 | |
| SCHEMBL3316192 | 0.95 | KDM4E (0.83) | KDM4EFABP4FABP5HDAC6HDAC1 | |
| SCHEMBL3322057 | 0.89 | KDM4E (1.00) | KDM4EFABP4FABP5HDAC6HDAC1 | |
| SCHEMBL12951764 | 0.86 | FABP4 (1.00) | KDM4EFABP4FABP5HDAC6HDAC1 | |
| SCHEMBL31156410 | 0.84 | FABP4 (0.97) | KDM4EFABP4FABP5HDAC6HDAC1 | |
| SCHEMBL29114062 | 0.84 | FABP4 (0.97) | KDM4EFABP4FABP5HDAC6HDAC1 | |
| SCHEMBL6419189 | 0.84 | FABP4 (0.97) | KDM4EFABP4FABP5HDAC6HDAC1 | |
| SCHEMBL12938804 | 0.84 | FABP4 (0.73) | KDM4EFABP4FABP5HDAC6HDAC1 | |
| SCHEMBL6833930 | 0.84 | FABP4 (0.97) | KDM4EFABP4FABP5HDAC6HDAC1 | |
| SCHEMBL12938815 | 0.83 | FABP4 (0.71) | KDM4EFABP4FABP5HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2456757-B1 | HDAC INHIBITORS AND THERAPEUTIC METHODS USING THE SAME | UNIV ILLINOIS (US) | 2019-05-01 | — | — | EP | disclosed |