Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 4/20 | 0.55 |
| ▸ | PDE4A | P27815 | 3/20 | 0.55 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.55 |
| ▸ | IKBKB | O14920 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 5/20 | 0.44 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12325398 | 0.98 | PDE4B (0.56) | PDE4BPDE4APDE4CPDE4DIKBKB | |
| SCHEMBL7169549 | 0.86 | IKBKB (0.48) | PDE4BPDE4APDE4CPDE4DIKBKB | |
| SCHEMBL12455941 | 0.85 | PDE4B (0.46) | PDE4BPDE4APDE4CPDE4DIKBKB | |
| SCHEMBL757781 | 0.84 | PDE4B (0.53) | PDE4BPDE4APDE4CPDE4DIKBKB | |
| SCHEMBL24238256 | 0.83 | PDE4B (0.56) | PDE4BPDE4APDE4CPDE4DIKBKB | |
| SCHEMBL29113865 | 0.83 | PDE4B (0.51) | PDE4BPDE4APDE4CPDE4DIKBKB | |
| SCHEMBL3686460 | 0.83 | BACE1 (0.62) | PDE4BPDE4APDE4CPDE4DBACE1 | |
| SCHEMBL25913140 | 0.83 | PDE4B (0.51) | PDE4BPDE4APDE4CPDE4DIKBKB | |
| SCHEMBL12299729 | 0.83 | PDE4B (0.51) | PDE4BPDE4APDE4CPDE4DIKBKB | |
| SCHEMBL19750886 | 0.83 | CYP1A1 (0.47) | PDE4BPDE4APDE4CPDE4DIKBKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11779911-B2 | Production of fatty olefin derivatives via olefin metathesis | PROVIVI, INC. (US) | 2023-10-10 | — | — | US | disclosed |
| US-20220032280-A1 | PRODUCTION OF FATTY OLEFIN DERIVATIVES VIA OLEFIN METATHESIS | PROVIVI, INC. (US) | 2022-02-03 | — | — | US | disclosed |
| EP-2771386-B1 | HYPERBRANCHED POLYMERS, METHODS FOR PRODUCING SAME, AND USE OF SAME IN ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2017-03-01 | — | — | EP | disclosed |
| EP-2566875-B1 | FORMULATIONS AND ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-01-06 | — | — | EP | disclosed |
| EP-2517277-B1 | COMPOSITION FOR THE PREPARATION OF ORGANIC ELECTRONIC (OE) DEVICES | MERCK PATENT GMBH (DE) | 2015-07-08 | — | — | EP | disclosed |
| WO-2015018480-A1 | FORMULATION FOR THE PREPARATION OF ORGANIC ELECTRONIC (OE) DEVICES COMPRISING A POLYMERIC BINDER | MERCK PATENT GMBH (DE) | 2015-02-12 | — | — | WO | disclosed |
| US-8163753-B2 | 2-(4-(4-(4-chlorophenyl)oxazol-2-yl)phenoxymethyl)-2-methyl-6-nitro-2,3-dihydroimidazo[2,1-b]oxazole; bactericide; excellent bactericidal action against Mycobacterium tuberculosis, multi-drug-resistant Mycobacterium tuberculosis, and atypical acid-fast bacteria | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2012-04-24 | — | — | US | disclosed |
| WO-2011137922-A1 | FORMULATIONS AND ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2011-11-10 | — | — | WO | disclosed |
| EP-1678185-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMA CO LTD (JP) | 2008-10-08 | — | — | EP | disclosed |
| US-20080119478-A1 | 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis | OTSUKA PHAMACEUTICAL CO., LTD. (JP) | 2008-05-22 | — | — | US | disclosed |
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119478-A1 | 2,3-Dihydro-6-Nitroimidazo (2,1-b) Oxazole Compounds for the Treatment of Tuberculosis | NR2C2, NR0B2, NR4A2 | PDE4B 2685/4885PDE4A 3611/4885PDE4C 3847/4885 |
| US-11779911-B2 | Production of fatty olefin derivatives via olefin metathesis | SREBF1, F2, SREBF2 | PDE4B 4120/4885PDE4A 4491/4885PDE4C 4323/4885 |
| US-20220032280-A1 | PRODUCTION OF FATTY OLEFIN DERIVATIVES VIA OLEFIN METATHESIS | SREBF1, F2, SREBF2 | PDE4B 4120/4885PDE4A 4491/4885PDE4C 4323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.