SCHEMBL209681

SCHEMBL209681

O=C(O)CNC(=O)C1CCCO1

nearest known ligand 0.49

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
POLB P06746 4/20 0.49
PKM P14618 2/20 0.49
ALPG P10696 1/20 0.48
HPGD P15428 4/20 0.46
ALDH1A1 P00352 2/20 0.46
TP53 P04637 2/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
TDP1 Q9NUW8 1/20 0.44
GAA P10253 1/20 0.44
GLS O94925 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8092787 0.81 POLB (0.42) POLBPKMALPGHPGDALDH1A1
SCHEMBL47294 0.79 POLB (0.50) POLBPKMALPGHPGDALDH1A1
SCHEMBL3270695 0.79 TSHR (0.51) POLBPKMALPGHPGDALDH1A1
SCHEMBL21941834 0.79 TSHR (0.51) POLBPKMALPGHPGDALDH1A1
SCHEMBL8203284 0.78 EGLN1 (0.38) POLBHPGDALDH1A1TDP1
SCHEMBL24177181 0.76 POLB (0.55) POLBPKMALPGHPGDALDH1A1
SCHEMBL1472587 0.76 POLB (0.55) POLBPKMALPGHPGDALDH1A1
SCHEMBL6360835 0.76 POLB (0.55) POLBPKMALPGHPGDALDH1A1
SCHEMBL5963073 0.76 POLB (0.48) POLBPKMALPGHPGDALDH1A1
SCHEMBL9484968 0.76 HPGD (0.49) POLBPKMALPGHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2094246-B1 SUSTAINED-RELEASE COMPOSITION AND METHOD FOR PRODUCING THE SAME TAKEDA PHARMACEUTICALS CO (JP) 2020-04-01 EP disclosed
US-9713595-B2 Sustained-release composition and method for producing the same TAKEDA PHARMACEUTICALS COMPANY LIMITED (JP) 2017-07-25 US disclosed
US-20170165204-A1 SUSTAINED-RELEASE COMPOSITION AND METHOD FOR PRODUCING THE SAME TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-06-15 US disclosed
US-9617303-B2 Sustained-release composition and method for producing the same TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2017-04-11 US disclosed
EP-1466596-B1 MICROSPHERE AND METHOD FOR PRODUCTION THEREOF TAKEDA PHARMACEUTICAL (JP) 2016-08-31 EP disclosed
US-20150080322-A1 SUSTAINED-RELEASE COMPOSITION AND METHOD FOR PRODUCING THE SAME TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2015-03-19 US disclosed
US-8927016-B2 Producing a sustained-release preparation TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2015-01-06 US disclosed
US-8921326-B2 Sustained-release composition and method for producing the same TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2014-12-30 US disclosed
US-8815801-B2 Controlled release composition and method of producing the same TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2014-08-26 US disclosed
US-20120295848-A1 SUSTAINED-RELEASE COMPOSITION AND PROCESS FOR PRODUCING THE SAME TAKEDA PHARMACEUTICAL COMPANY LIMITED 2012-11-22 US disclosed
US-20040077531-A1 Use of galanin-like peptide TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-04-22 US disclosed
EP-1360964-A1 USE OF GALANIN-LIKE PEPTIDE Takeda Chemical Industries, Ltd. (JP) 2003-11-12 EP disclosed
EP-1330293-A2 CONTROLLED RELEASE COMPOSITION COMPRISING LACTIC ACID POLYMER AND HYDROXYNAPHTHOIC ACID, AND METHOD OF PRODUCING THE SAME Takeda Chemical Industries, Ltd. (JP) 2003-07-30 EP disclosed
US-20030134800-A1 Controlled release composition and method of producing the same TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2003-07-17 US disclosed
EP-1049458-B1 LYOPHILIZATION METHOD FOR SUSTAINED-RELEASE PREPARATIONS TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2003-03-26 EP disclosed
WO-2003002092-A2 CONTROLLED RELEASE COMPOSITION COMPRISING LACTIC ACID POLYMER AND HYDROXYNAPHTHOIC ACID, AND METHOD OF PRODUCING THE SAME TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2003-01-09 WO disclosed
EP-1197208-A1 SUSTAINED RELEASE COMPOSITIONS, PROCESS FOR PRODUCING THE SAME AND USE THEREOF Takeda Chemical Industries, Ltd. (JP) 2002-04-17 EP disclosed
EP-1158014-A1 PROCESS FOR PRODUCING POLYMER Takeda Chemical Industries, Ltd. (JP) 2001-11-28 EP disclosed
EP-1136079-A1 AGENTS FOR RETARDING CHANGE OF HORMONE-DEPENDENT CANCER INTO HORMONE-INDEPENDENT CANCER Takeda Chemical Industries, Ltd. (JP) 2001-09-26 EP disclosed
EP-1048301-A1 SUSTAINED RELEASE COMPOSITIONS, PROCESS FOR PRODUCING THE SAME AND UTILIZATION THEREOF Takeda Chemical Industries, Ltd. (JP) 2000-11-02 EP disclosed