Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27806423 | 0.82 | POLB (0.52) | POLBPKMALPGHPGDALDH1A1 | |
| SCHEMBL3270695 | 0.81 | TSHR (0.51) | POLBPKMALPGHPGDALDH1A1 | |
| SCHEMBL21941834 | 0.81 | TSHR (0.51) | POLBPKMALPGHPGDALDH1A1 | |
| SCHEMBL22170895 | 0.80 | POLB (0.50) | POLBPKMALPGHPGDALDH1A1 | |
| SCHEMBL209681 | 0.79 | POLB (0.49) | POLBPKMALPGHPGDALDH1A1 | |
| SCHEMBL24177181 | 0.78 | POLB (0.55) | POLBPKMALPGHPGDALDH1A1 | |
| SCHEMBL1472587 | 0.78 | POLB (0.55) | POLBPKMALPGHPGDALDH1A1 | |
| SCHEMBL5963073 | 0.78 | POLB (0.48) | POLBPKMALPGHPGDALDH1A1 | |
| SCHEMBL6360835 | 0.78 | POLB (0.55) | POLBPKMALPGHPGDALDH1A1 | |
| SCHEMBL9484968 | 0.78 | HPGD (0.49) | POLBPKMALPGHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2582696-B1 | 5-ARYL ISOXAZOLINES FOR CONTROLLING PESTS | NOVARTIS AG (CH) | 2014-10-22 | — | — | EP | disclosed |
| WO-2012120135-A1 | ISOXAZOLE DERIVATIVES | NOVARTIS AG (CH) | 2012-09-13 | — | — | WO | disclosed |
| WO-2011157748-A1 | 5-ARYL ISOXAZOLINES FOR CONTROLLING PESTS | NOVARTIS AG (CH) | 2011-12-22 | — | — | WO | disclosed |