SCHEMBL20969043

SCHEMBL20969043

CC(C)(C)[Si](C)(C)Cl.[SiH3]Cl

nearest known ligand 0.39

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL595 0.91
SCHEMBL20873161 0.91 ALDH1A1 (0.46) ALDH1A1
Hydrochloric Acid SCHEMBL22319895 0.87
Methane SCHEMBL28876184 0.87
Potassium SCHEMBL31236839 0.87
SCHEMBL9871519 0.87 ALDH1A1 (0.55) ALDH1A1
SCHEMBL1162396 0.87
SCHEMBL29800731 0.87
Iodide SCHEMBL8063167 0.83 ALDH1A1 (0.39) ALDH1A1
Methyl Alcohol SCHEMBL18730123 0.83 ALDH1A1 (0.39) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3129025-B1 PROCESS FOR THE MANUFACTURING OF MEDICAMENTS GENENTECH INC (US) 2019-05-15 EP claimed
CN-105873916-B Amide derivatives for GPR119 agonists 株式会社钟根堂 2019-08-27 CN disclosed
CN-110028494-A Amide derivatives, its stereoisomer or its pharmaceutically acceptable salt and the pharmaceutical composition comprising it 株式会社钟根堂 2019-07-19 CN disclosed
CN-105873916-A Amide derivatives for GPR119 agonists 株式会社钟根堂 2016-08-17 CN disclosed
CN-103402977-A Ingenol-3-acylate III and Ingenol-3-carbamate LEO PHARMA AS 2013-11-20 CN disclosed