Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538590 | 1.00 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2ANPC1HPGD | |
| SCHEMBL20969496 | 1.00 | ALDH1A1 (0.70) | ALDH1A1MEN1KMT2ANPC1HPGD | |
| SCHEMBL20678578 | 0.86 | ALDH1A1 (0.72) | ALDH1A1MEN1KMT2ANPC1HPGD | |
| Carvone SCHEMBL18305510 | 0.82 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2ANPC1HPGD | |
| Carvone SCHEMBL39408 | 0.82 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2ANPC1HPGD | |
| (S)(+)Carvone SCHEMBL184022 | 0.82 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2ANPC1HPGD | |
| Carvone SCHEMBL19899318 | 0.82 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2ANPC1HPGD | |
| L-Carvone SCHEMBL230994 | 0.82 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2ANPC1HPGD | |
| Carvone SCHEMBL2036234 | 0.82 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2ANPC1HPGD | |
| Carvone SCHEMBL18497397 | 0.82 | ALDH1A1 (0.90) | ALDH1A1MEN1KMT2ANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190127306-A1 | POLYCYCLIC CARBOGENIC MOLECULES AND USES THEREOF AS ANTI-CANCER AGENTS | NORTHWESTERN UNIVERSITY (US) | 2019-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190127306-A1 | POLYCYCLIC CARBOGENIC MOLECULES AND USES THEREOF AS ANTI-CANCER AGENTS | MYC, CDK4, CDKL3 | ALDH1A1 2424/4885MEN1 1952/4885KMT2A 2265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.